UniProt P14891
3-hydroxy-3-methylglutaryl-coenzyme A reductase 1 (P14891)
3-hydroxy-3-methylglutaryl-coenzyme A reductase 1 (UniProt P14891), EC 1.1.1.34: 2 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound. Binding sites, druggability and experiment against prediction…
- UniProt
- P14891
- Protein
- 3-hydroxy-3-methylglutaryl-coenzyme A reductase 1
- EC
- 1.1.1.34
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 1
Structures
3 records of P14891 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7ULI | Apo HMG-CoA Reductase from Arabidopsis thaliana (HMG1) | x-ray diffraction | AAA | — | — |
| 8ECG | Complex of HMG1 with pitavastatin | x-ray diffraction | A | PV9 | — |
| P14891 | AlphaFold monomer V2.0 prediction for 3-hydroxy-3-methylglutaryl- coenzyme a reductase 1 (P14891) | predicted | A | — | — |
Ligands
- PV9 · Pitavastatin · in 1 record
Experiment against prediction
- 8ECG chain A against the predicted model P14891: TM-score 0.99, RMSD 0.80 Å
- 7ULI chain AAA against the predicted model P14891: TM-score 0.99, RMSD 0.83 Å
Elsewhere
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