UniProt P14832
Peptidyl-prolyl cis-trans isomerase (P14832)
Peptidyl-prolyl cis-trans isomerase (UniProt P14832), EC 5.2.1.8: 7 experimental structures and 1 predicted model on GenesisL1, 7 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P14832
- Protein
- Peptidyl-prolyl cis-trans isomerase
- EC
- 5.2.1.8
- Experimental structures
- 7
- Predicted models
- 1
- Pockets
- 7 · 3 records with a druggable one
Structures
8 records of P14832 in the MolNFT archive: 7 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1IST | Crystal structure of yeast cyclophilin A, CPR1 | x-ray diffraction | A, B | — | — |
| 1IST | Crystal structure of yeast cyclophilin a, CPR1 | x-ray diffraction | A, B | — | — |
| 1VDN | Crystal Structure Of Yeast Cyclophilin A Complexed With ACE-Ala-Ala-Pro-Ala-7-Amino-4-Methylcoumarin | x-ray diffraction | A | — | — |
| 1VDN | Crystal structure of yeast cyclophilin a complexed with ACE-ala-ala… | x-ray diffraction | A | — | — |
| 9CF0 | Parasitella parasitica Fanzor (PpFz) State 1 | electron microscopy | C | — | 2 (best 0.67) |
| 9CF2 | Parasitella parasitica Fanzor (PpFz) State 3 | electron microscopy | C | — | 2 (best 0.68) |
| 9CF3 | Parasitella parasitica Fanzor (PpFz) State 4 | electron microscopy | C | — | 3 (best 0.67) |
| P14832 | AlphaFold monomer V2.0 prediction for peptidyl-prolyl cis-trans isomerase (P14832) | predicted | A | — | — |
Experiment against prediction
- 1IST chain A against the predicted model P14832: TM-score 1.00, RMSD 0.31 Å
- 1IST chain A against the predicted model P14832: TM-score 1.00, RMSD 0.31 Å
- 1VDN chain A against the predicted model P14832: TM-score 1.00, RMSD 0.33 Å
- 1VDN chain A against the predicted model P14832: TM-score 1.00, RMSD 0.33 Å
- 1IST chain B against the predicted model P14832: TM-score 0.99, RMSD 0.35 Å
- 1IST chain B against the predicted model P14832: TM-score 0.99, RMSD 0.35 Å
- 9CF3 chain C against the predicted model P14832: TM-score 0.99, RMSD 0.51 Å
- 9CF0 chain C against the predicted model P14832: TM-score 0.99, RMSD 0.52 Å
- 9CF2 chain C against the predicted model P14832: TM-score 0.98, RMSD 0.59 Å
Elsewhere
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