UniProt P14741
Translation initiation factor eIF-2B subunit alpha (P14741)
Translation initiation factor eIF-2B subunit alpha (UniProt P14741): 16 experimental structures and 1 predicted model on GenesisL1, 78 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P14741
- Protein
- Translation initiation factor eIF-2B subunit alpha
- Experimental structures
- 16
- Predicted models
- 1
- Pockets
- 78 · 8 records with a druggable one
Structures
17 records of P14741 in the MolNFT archive: 16 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6I3M | eIF2B:eIF2 complex, phosphorylated on eIF2 alpha serine 52. | electron microscopy | A, B | — | 9 (best 0.89) |
| 6I3M | EIF2B:EIF2 complex, phosphorylated on EIF2 alpha serine 52. | electron microscopy | A, B | — | — |
| 6I7T | eIF2B:eIF2 complex | electron microscopy | A, B | — | 7 (best 0.87) |
| 6I7T | EIF2B:EIF2 complex | electron microscopy | A, B | — | — |
| 6QG0 | Structure of eIF2B-eIF2 (phosphorylated at Ser51) complex (model 1) | electron microscopy | A, B | — | 10 (best 0.85) |
| 6QG0 | Structure of EIF2B-EIF2 (phosphorylated at SER51) complex (model 1) | electron microscopy | A, B | — | — |
| 6QG1 | Structure of eIF2B-eIF2 (phosphorylated at Ser51) complex (model 2) | electron microscopy | A, B | — | 9 (best 0.87) |
| 6QG1 | Structure of EIF2B-EIF2 (phosphorylated at SER51) complex (model 2) | electron microscopy | A, B | — | — |
| 6QG2 | Structure of eIF2B-eIF2 (phosphorylated at Ser51) complex (model A) | electron microscopy | A, B | — | 11 (best 0.87) |
| 6QG2 | Structure of EIF2B-EIF2 (phosphorylated at SER51) complex (model a) | electron microscopy | A, B | — | — |
| 6QG3 | Structure of eIF2B-eIF2 (phosphorylated at Ser51) complex (model B) | electron microscopy | A, B | — | 11 (best 0.89) |
| 6QG3 | Structure of EIF2B-EIF2 (phosphorylated at SER51) complex (model B) | electron microscopy | A, B | — | — |
| 6QG5 | Structure of eIF2B-eIF2 (phosphorylated at Ser51) complex (model C) | electron microscopy | A, B | — | 10 (best 0.87) |
| 6QG5 | Structure of EIF2B-EIF2 (phosphorylated at SER51) complex (model C) | electron microscopy | A, B | — | — |
| 6QG6 | Structure of eIF2B-eIF2 (phosphorylated at Ser51) complex (model D) | electron microscopy | A, B | — | 11 (best 0.88) |
| 6QG6 | Structure of EIF2B-EIF2 (phosphorylated at SER51) complex (model D) | electron microscopy | A, B | — | — |
| P14741 | AlphaFold monomer V2.0 prediction for translation initiation factor eif-2B subunit alpha (P14741) | predicted | A | — | — |
Experiment against prediction
- 6QG1 chain A against the predicted model P14741: TM-score 0.91, RMSD 2.23 Å
- 6QG1 chain A against the predicted model P14741: TM-score 0.91, RMSD 2.23 Å
- 6QG0 chain A against the predicted model P14741: TM-score 0.91, RMSD 2.23 Å
- 6QG0 chain A against the predicted model P14741: TM-score 0.91, RMSD 2.23 Å
- 6QG0 chain B against the predicted model P14741: TM-score 0.91, RMSD 2.24 Å
- 6QG0 chain B against the predicted model P14741: TM-score 0.91, RMSD 2.24 Å
- 6QG1 chain B against the predicted model P14741: TM-score 0.91, RMSD 2.24 Å
- 6QG1 chain B against the predicted model P14741: TM-score 0.91, RMSD 2.24 Å
- 6I7T chain B against the predicted model P14741: TM-score 0.91, RMSD 2.23 Å
- 6I7T chain B against the predicted model P14741: TM-score 0.91, RMSD 2.23 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.