UniProt P14740
P14740
P14740 (UniProt P14740): 17 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P14740
- Experimental structures
- 17
- Predicted models
- 1
- Ligands
- 2
Structures
18 records of P14740 in the MolNFT archive: 17 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2GBC | Native DPP-IV (CD26) from Rat | x-ray diffraction | A, B | — | — |
| 2GBC | Native dpp-IV (CD26) from rat | x-ray diffraction | A, B | — | — |
| 2GBF | rat dpp-IV with alkynyl cyanopyrrolidine #1 | x-ray diffraction | A, B | — | — |
| 2GBF | Rat dpp-IV with alkynyl cyanopyrrolidine #1 | x-ray diffraction | A, B | — | — |
| 2GBG | rat DPP-IV with alkynyl cyanopyrrolidine #2 | x-ray diffraction | A, B | — | — |
| 2GBG | Rat dpp-IV with alkynyl cyanopyrrolidine #2 | x-ray diffraction | A, B | — | — |
| 2GBI | rat DPP-IV with xanthine inhibitor 4 | x-ray diffraction | A, B | — | — |
| 2GBI | Rat dpp-IV with xanthine inhibitor 4 | x-ray diffraction | A, B | — | — |
| 2I3Z | rat DPP-IV with xanthine mimetic inhibitor #7 | x-ray diffraction | A, B | — | — |
| 2I3Z | Rat dpp-IV with xanthine mimetic inhibitor #7 | x-ray diffraction | A, B | — | — |
| 2OAE | Crystal structure of rat dipeptidyl peptidase (DPPIV) with thiazole-based peptide mimetic #31 | x-ray diffraction | A, B | — | — |
| 2OAE | Crystal structure of rat dipeptidyl peptidase (dppiv) with thiazole- based peptide mimetic #31 | x-ray diffraction | A, B | — | — |
| 4FFV | Crystal Structure of Dipeptidyl Peptidase IV (DPP4, DPP-IV, CD26) in Complex with 11A19 Fab | x-ray diffraction | A, B | — | — |
| 4FFV | Crystal structure of dipeptidyl peptidase IV (DPP4, dpp-IV, CD26) in complex with 11A19 Fab | x-ray diffraction | A, B | — | — |
| 4FFW | Crystal Structure of Dipeptidyl Peptidase IV (DPP4, DPP-IV, CD26) in Complex with Fab + sitagliptin | x-ray diffraction | A, B | — | — |
| 4FFW | Crystal structure of dipeptidyl peptidase IV (DPP4, dpp-IV, CD26) in complex with Fab + sitagliptin | x-ray diffraction | A, B | — | — |
| 5VTA | Co-crystal structure of dppiv with a chemibody inhibitor | x-ray diffraction | A, B, C, D | NAG, 9K4 | — |
| P14740 | AlphaFold monomer V2.0 prediction for dipeptidyl peptidase 4 (P14740) | predicted | A | — | — |
Ligands
Experiment against prediction
- 5VTA chain B against the predicted model P14740: TM-score 1.00, RMSD 0.58 Å
- 5VTA chain A against the predicted model P14740: TM-score 1.00, RMSD 0.62 Å
- 5VTA chain D against the predicted model P14740: TM-score 1.00, RMSD 0.68 Å
- 2GBG chain B against the predicted model P14740: TM-score 0.99, RMSD 0.70 Å
- 2GBG chain B against the predicted model P14740: TM-score 0.99, RMSD 0.70 Å
- 2GBG chain A against the predicted model P14740: TM-score 0.99, RMSD 0.70 Å
- 2GBG chain A against the predicted model P14740: TM-score 0.99, RMSD 0.70 Å
- 2GBC chain B against the predicted model P14740: TM-score 0.99, RMSD 0.70 Å
- 2GBC chain B against the predicted model P14740: TM-score 0.99, RMSD 0.70 Å
- 2GBC chain A against the predicted model P14740: TM-score 0.99, RMSD 0.70 Å
Elsewhere
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