UniProt P14736
DNA repair protein RAD4 (P14736)
DNA repair protein RAD4 (UniProt P14736): 20 experimental structures and 1 predicted model on GenesisL1, 19 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P14736
- Protein
- DNA repair protein RAD4
- Experimental structures
- 20
- Predicted models
- 1
- Pockets
- 19 · 3 records with a druggable one
Structures
21 records of P14736 in the MolNFT archive: 20 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2M14 | NMR structure of the complex between the PH domain of the Tfb1 subunit from TFIIH and Rad4 | solution nmr | B | — | — |
| 2M14 | NMR structure of the complex between the pH domain of the TFB1 subunit from tfiih and RAD4 | solution nmr | B | — | — |
| 2QSF | Crystal structure of the Rad4-Rad23 complex | x-ray diffraction | A | — | — |
| 2QSF | Crystal structure of the RAD4-RAD23 complex | x-ray diffraction | A | — | — |
| 2QSG | Crystal structure of Rad4-Rad23 bound to a UV-damaged DNA | x-ray diffraction | A | — | — |
| 2QSG | Crystal structure of RAD4-RAD23 bound to a UV-damaged DNA | x-ray diffraction | A | — | — |
| 2QSH | Crystal structure of Rad4-Rad23 bound to a mismatch DNA | x-ray diffraction | A | — | — |
| 2QSH | Crystal structure of RAD4-RAD23 bound to a mismatch DNA | x-ray diffraction | A | — | — |
| 4YIR | Crystal structure of Rad4-Rad23 crosslinked to an undamaged DNA | x-ray diffraction | A | — | — |
| 4YIR | Crystal structure of RAD4-RAD23 crosslinked to an undamaged DNA | x-ray diffraction | A | — | — |
| 6CFI | Crystal structure of Rad4-Rad23 bound to a 6-4 photoproduct UV lesion | x-ray diffraction | A | — | — |
| 6CFI | Crystal structure of RAD4-RAD23 bound to a 6-4 photoproduct UV lesion | x-ray diffraction | A | — | — |
| 6UBF | Role of Beta-hairpin motifs in the DNA duplex opening by the Rad4/XPC nucleotide excision repair… | x-ray diffraction | A | — | 7 (best 0.79) |
| 6UBF | Role of beta-hairpin motifs in the DNA duplex opening by the RAD4/XPC nucleotide excision repair… | x-ray diffraction | A | — | — |
| 6UG1 | Sequence impact in DNA duplex opening by the RAD4/XPC nucleotide excision repair complex | x-ray diffraction | A | — | — |
| 6UIN | Role of Beta-hairpin motifs in the DNA duplex opening by the Rad4/XPC nucleotide excision repair… | x-ray diffraction | A | — | 6 (best 0.75) |
| 6UIN | Role of beta-hairpin motifs in the DNA duplex opening by the RAD4/XPC nucleotide excision repair… | x-ray diffraction | A | — | — |
| 7K04 | Structure of TFIIH/RAD4-RAD23-RAD33/DNA in DNA opening | electron microscopy | A | — | — |
| 7M2U | Nucleotide Excision Repair complex TFIIH Rad4-33 | electron microscopy | A | — | — |
| 7M2U | Nucleotide excision repair complex tfiih RAD4-33 | electron microscopy | A | — | — |
| P14736 | AlphaFold monomer V2.0 prediction for DNA repair protein RAD4 (P14736) | predicted | A | — | 6 (best 0.72) |
Experiment against prediction
- 2QSH chain A against the predicted model P14736: TM-score 0.99, RMSD 1.08 Å
- 2QSH chain A against the predicted model P14736: TM-score 0.99, RMSD 1.08 Å
- 2QSG chain A against the predicted model P14736: TM-score 0.98, RMSD 1.28 Å
- 2QSG chain A against the predicted model P14736: TM-score 0.98, RMSD 1.28 Å
- 6UBF chain A against the predicted model P14736: TM-score 0.98, RMSD 1.31 Å
- 6UBF chain A against the predicted model P14736: TM-score 0.98, RMSD 1.31 Å
- 6UIN chain A against the predicted model P14736: TM-score 0.98, RMSD 1.27 Å
- 6UIN chain A against the predicted model P14736: TM-score 0.98, RMSD 1.27 Å
- 4YIR chain A against the predicted model P14736: TM-score 0.97, RMSD 1.44 Å
- 4YIR chain A against the predicted model P14736: TM-score 0.97, RMSD 1.44 Å
Elsewhere
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