UniProt P14635
G2/mitotic-specific cyclin-B1 (P14635)
G2/mitotic-specific cyclin-B1 (UniProt P14635): 18 experimental structures and 1 predicted model on GenesisL1. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P14635
- Protein
- G2/mitotic-specific cyclin-B1
- Experimental structures
- 18
- Predicted models
- 1
Structures
19 records of P14635 in the MolNFT archive: 18 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2B9R | Crystal Structure of Human Cyclin B1 | x-ray diffraction | A, B | — | — |
| 2B9R | Crystal structure of human cyclin B1 | x-ray diffraction | A, B | — | — |
| 2JGZ | Crystal structure of phospho-CDK2 in complex with Cyclin B | x-ray diffraction | B | — | — |
| 2JGZ | Crystal structure of phospho-CDK2 in complex with cyclin B | x-ray diffraction | B | — | — |
| 4Y72 | Human CDK1/CyclinB1/CKS2 With Inhibitor | x-ray diffraction | B | — | — |
| 4Y72 | Human CDK1/CYCLINB1/CKS2 with inhibitor | x-ray diffraction | B | — | — |
| 4YC3 | CDK1/CyclinB1/CKS2 Apo | x-ray diffraction | B | — | — |
| 4YC3 | CDK1/CYCLINB1/CKS2 apo | x-ray diffraction | B | — | — |
| 5HQ0 | Ternary complex of human proteins CDK1, Cyclin B and CKS2, bound to an inhibitor | x-ray diffraction | B | — | — |
| 5HQ0 | Ternary complex of human proteins CDK1, cyclin B and CKS2, bound to an inhibitor | x-ray diffraction | B | — | — |
| 5LQF | CDK1/CyclinB1/CKS2 in complex with NU6102 | x-ray diffraction | B, E | — | — |
| 5LQF | CDK1/CYCLINB1/CKS2 in complex with NU6102 | x-ray diffraction | B, E | — | — |
| 6GU2 | CDK1/CyclinB/Cks2 in complex with Flavopiridol | x-ray diffraction | B | — | — |
| 6GU2 | CDK1/CYCLINB/CKS2 in complex with flavopiridol | x-ray diffraction | B | — | — |
| 6GU3 | CDK1/CYCLINB/CKS2 in complex with AZD5438 | x-ray diffraction | B | — | — |
| 6GU4 | CDK1/CYCLINB/CKS2 in complex with CGP74514A | x-ray diffraction | B | — | — |
| 7NJ0 | Cryoem structure of the human separase-CDK1-cyclin B1-CKS1 complex | electron microscopy | C | — | — |
| 8TAU | APC/C-CDH1-UBE2C-UBE2S-Ubiquitin-CyclinB | electron microscopy | B | — | — |
| P14635 | AlphaFold monomer V2.0 prediction for G2/MITOTIC-specific cyclin-B1 (P14635) | predicted | A | — | — |
Experiment against prediction
- 6GU2 chain B against the predicted model P14635: TM-score 0.99, RMSD 0.63 Å
- 6GU2 chain B against the predicted model P14635: TM-score 0.99, RMSD 0.63 Å
- 2JGZ chain B against the predicted model P14635: TM-score 0.99, RMSD 0.62 Å
- 2JGZ chain B against the predicted model P14635: TM-score 0.99, RMSD 0.62 Å
- 5LQF chain E against the predicted model P14635: TM-score 0.99, RMSD 0.66 Å
- 5LQF chain E against the predicted model P14635: TM-score 0.99, RMSD 0.66 Å
- 7NJ0 chain C against the predicted model P14635: TM-score 0.99, RMSD 0.65 Å
- 6GU4 chain B against the predicted model P14635: TM-score 0.99, RMSD 0.68 Å
- 5LQF chain B against the predicted model P14635: TM-score 0.99, RMSD 0.70 Å
- 5LQF chain B against the predicted model P14635: TM-score 0.99, RMSD 0.70 Å
Elsewhere
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