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UniProt P14625

Endoplasmin (P14625)

Endoplasmin (UniProt P14625): 3 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 7 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.

UniProt
P14625
Protein
Endoplasmin
Experimental structures
3
Predicted models
1
Ligands
2
Pockets
7 · 3 records with a druggable one

Structures

4 records of P14625 in the MolNFT archive: 3 experimental, 1 predicted.

EntryTitleMethodChainsLigandsPockets
4NH9Correlation between chemotype-dependent binding conformations of HSP90 alpha/beta and isoform…x-ray diffractionA2LC1 (best 0.61)
4NH9Correlation between chemotype-dependent binding conformations of HSP90 ALPHA/BETA and isoform…x-ray diffractionA2LC1 (best 0.61)
7ULLHuman Grp94 N-terminal domain in complex with 42Cx-ray diffractionA, B42C5 (best 0.66)
P14625AlphaFold monomer V2.0 prediction for endoplasmin (P14625)predictedA——

Ligands

  • 2LC · 2-fluoro-6-[(3S)-tetrahydrofuran-3-ylamino]-4-(3,6,6-trimethyl-4-oxo-4,5,6,7-tetrahydro-1H-indol-1-yl)benzamide · in 2 records
  • 42C · N,N-dimethyl-7H-purin-6-amine · in 1 record

Experiment against prediction

Elsewhere

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