UniProt P14438
H-2 class II histocompatibility antigen, A-U alpha chain (P14438)
H-2 class II histocompatibility antigen, A-U alpha chain (UniProt P14438): 10 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 54 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- P14438
- Protein
- H-2 class II histocompatibility antigen, A-U alpha chain
- Experimental structures
- 10
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 54 · 6 records with a druggable one
Structures
11 records of P14438 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1K2D | Crystal structure of the autoimmune MHC class II I-Au complexed with myelin basic protein 1-11 at… | x-ray diffraction | A | NAG | 3 (best 0.48) |
| 1K2D | Crystal structure of the autoimmune MHC class II I-au complexed with myelin basic protein 1-11 at… | x-ray diffraction | A | NAG | 3 (best 0.48) |
| 1U3H | Crystal structure of mouse TCR 172.10 complexed with MHC class II I-Au molecule at 2.4 A | x-ray diffraction | C, G | — | 9 (best 0.51) |
| 1U3H | Crystal structure of mouse TCR 172.10 complexed with MHC class II I-au molecule at 2.4 a | x-ray diffraction | C, G | — | 9 (best 0.51) |
| 2P24 | I-Au/MBP125-135 | x-ray diffraction | A | — | 4 (best 0.44) |
| 2P24 | I-AU/MBP125-135 | x-ray diffraction | A | — | 4 (best 0.44) |
| 2PXY | Crystal structures of immune receptor complexes | x-ray diffraction | C | — | 6 (best 0.58) |
| 2PXY | Crystal structures of immune receptor complexes | x-ray diffraction | C | — | 6 (best 0.58) |
| 2Z31 | Crystal structure of immune receptor complex | x-ray diffraction | C | — | 4 (best 0.52) |
| 2Z31 | Crystal structure of immune receptor complex | x-ray diffraction | C | — | 4 (best 0.52) |
| P14438 | AlphaFold monomer V2.0 prediction for H-2 class II histocompatibility antigen, a-U alpha chain… | predicted | A | — | 2 (best 0.40) |
Ligands
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 2 records
Experiment against prediction
- 1U3H chain C against the predicted model P14438: TM-score 0.98, RMSD 0.34 Å
- 1U3H chain C against the predicted model P14438: TM-score 0.98, RMSD 0.34 Å
- 2P24 chain A against the predicted model P14438: TM-score 0.98, RMSD 0.36 Å
- 2P24 chain A against the predicted model P14438: TM-score 0.98, RMSD 0.36 Å
- 1K2D chain A against the predicted model P14438: TM-score 0.98, RMSD 0.38 Å
- 1K2D chain A against the predicted model P14438: TM-score 0.98, RMSD 0.38 Å
- 2Z31 chain C against the predicted model P14438: TM-score 0.97, RMSD 0.47 Å
- 2Z31 chain C against the predicted model P14438: TM-score 0.97, RMSD 0.47 Å
- 2PXY chain C against the predicted model P14438: TM-score 0.97, RMSD 0.38 Å
- 2PXY chain C against the predicted model P14438: TM-score 0.97, RMSD 0.38 Å
Elsewhere
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