UniProt P13612
Integrin alpha-4 (P13612)
Integrin alpha-4 (UniProt P13612): 8 experimental structures and 1 predicted model on GenesisL1, 1 pocket. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P13612
- Protein
- Integrin alpha-4
- Experimental structures
- 8
- Predicted models
- 1
- Pockets
- 1 · 0 records with a druggable one
Structures
9 records of P13612 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3V4P | crystal structure of a4b7 headpiece complexed with Fab ACT-1 | x-ray diffraction | A, C | — | — |
| 3V4P | Crystal structure of A4B7 headpiece complexed with Fab act-1 | x-ray diffraction | A, C | — | — |
| 3V4V | crystal structure of a4b7 headpiece complexed with Fab ACT-1 and RO0505376 | x-ray diffraction | A, C | — | — |
| 3V4V | Crystal structure of A4B7 headpiece complexed with Fab act-1 and RO0505376 | x-ray diffraction | A, C | — | — |
| 4HKC | 14-3-3-zeta in complex with S1011 phosphorylated integrin alpha-4 peptide | x-ray diffraction | B | — | — |
| 4HKC | 14-3-3-zeta in complex with S1011 phosphorylated integrin alpha-4 peptide | x-ray diffraction | B | — | — |
| 5C7Z | AP2 Mu2 adaptin C-terminal domain complexed with integrin alpha-4 peptide | x-ray diffraction | B | — | 1 (best 0.37) |
| 5C7Z | AP2 MU2 adaptin C-terminal domain complexed with integrin alpha-4 peptide | x-ray diffraction | B | — | — |
| P13612 | AlphaFold monomer V2.0 prediction for integrin alpha-4 (P13612) | predicted | A | — | — |
Experiment against prediction
- 3V4P chain C against the predicted model P13612: TM-score 0.93, RMSD 2.42 Å
- 3V4P chain C against the predicted model P13612: TM-score 0.93, RMSD 2.42 Å
- 3V4P chain A against the predicted model P13612: TM-score 0.91, RMSD 2.94 Å
- 3V4P chain A against the predicted model P13612: TM-score 0.91, RMSD 2.94 Å
- 3V4V chain A against the predicted model P13612: TM-score 0.90, RMSD 3.08 Å
- 3V4V chain A against the predicted model P13612: TM-score 0.90, RMSD 3.08 Å
- 3V4V chain C against the predicted model P13612: TM-score 0.88, RMSD 3.68 Å
- 3V4V chain C against the predicted model P13612: TM-score 0.88, RMSD 3.68 Å
- 5C7Z chain B against the predicted model P13612: TM-score 0.73, RMSD 0.34 Å
- 5C7Z chain B against the predicted model P13612: TM-score 0.73, RMSD 0.34 Å
Elsewhere
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