UniProt P13491
L-lactate dehydrogenase A chain (P13491)
L-lactate dehydrogenase A chain (UniProt P13491), EC 1.1.1.27: 20 experimental structures on GenesisL1, 5 ligands bound, 60 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P13491
- Protein
- L-lactate dehydrogenase A chain
- EC
- 1.1.1.27
- Experimental structures
- 20
- Predicted models
- 0
- Ligands
- 5
- Pockets
- 60 · 3 records with a druggable one
Structures
20 records of P13491 in the MolNFT archive: 20 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3H3F | Rabbit muscle L-lactate dehydrogenase in complex with NADH and oxamate | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 3H3F | Rabbit muscle L-lactate dehydrogenase in complex with NADH and oxamate | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 4I8X | Crystal structure of rabbit LDHA in complex with AP27460 | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 4I8X | Crystal structure of rabbit ldha in complex with AP27460 | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 4I9H | Crystal structure of rabbit LDHA in complex with AP28669 | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 4I9H | Crystal structure of rabbit ldha in complex with AP28669 | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 4I9N | Crystal structure of rabbit LDHA in complex with AP28161 and AP28122 | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 4I9N | Crystal structure of rabbit ldha in complex with AP28161 and AP28122 | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 4I9U | Crystal structure of rabbit LDHA in complex with a fragment inhibitor AP26256 | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 4I9U | Crystal structure of rabbit ldha in complex with a fragment inhibitor AP26256 | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 5KKC | l-lactate dehydrogenase from rabbit muscle with the inhibitor 6DHNAD | x-ray diffraction | A, B, C, D | 6V0, SO4 | 20 (best 0.89) |
| 5KKC | L-lactate dehydrogenase from rabbit muscle with the inhibitor 6DHNAD | x-ray diffraction | A, B, C, D | 6V0, SO4 | — |
| 5NQB | Rabbit Muscle L-lactate dehydrogenase in complex with malonate | x-ray diffraction | A, B, C, D | — | 20 (best 0.89) |
| 5NQB | Rabbit muscle L-lactate dehydrogenase in complex with malonate | x-ray diffraction | A, B, C, D | — | — |
| 5NQQ | Rabbit Muscle L-lactate dehydrogenase in complex with NADH and oxaloacetate | x-ray diffraction | A, B, C, D | NAI, SO4, OAA | — |
| 5NQQ | Rabbit muscle L-lactate dehydrogenase in complex with NADH and oxaloacetate | x-ray diffraction | A, B, C, D | NAI, SO4, OAA | — |
| 6P6U | Crystal structure of monoclinic rabbit muscle lactate dehydrogenase with four tetramers as the… | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P | AMP | — |
| 7P4G | Rabbit Muscle L-lactate dehydrogenase in complex with citrate | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P | — | 20 (best 0.89) |
| 7P4G | Rabbit muscle L-lactate dehydrogenase in complex with citrate | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P | — | — |
| P13491 | AlphaFold monomer V2.0 prediction for L-lactate dehydrogenase a chain (P13491) | — | — | — |
Ligands
- SO4 · Sulfate ion · in 4 records
- 6V0 · [[(2~{R},3~{S},4~{R},5~{R})-5-(5-aminocarbonyl-2~{H}-pyridin-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate · in 2 records
- NAI · 1,4-dihydronicotinamide adenine dinucleotide · in 2 records
- OAA · Oxaloacetate ion · in 2 records
- AMP · Adenosine monophosphate · in 1 record
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.