UniProt P12838
Neutrophil defensin 4 (P12838)
Neutrophil defensin 4 (UniProt P12838): 5 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P12838
- Protein
- Neutrophil defensin 4
- Experimental structures
- 5
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 3 · 1 record with a druggable one
Structures
6 records of P12838 in the MolNFT archive: 5 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1ZMM | Crystal structure of human alpha-defensin-4 | x-ray diffraction | A, B, C, D | — | — |
| 1ZMM | Crystal structure of human alpha-defensin-4 | x-ray diffraction | A, B, C, D | — | — |
| 6DMM | Crystal structure of the G23A mutant of human alpha defensin HNP4. | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L | SO4 | — |
| 6DMQ | Crystal structure of the T27A mutant of human alpha defensin HNP4. | x-ray diffraction | A, B, C, D, E, F, G, H | — | 3 (best 0.53) |
| 6DMQ | Crystal structure of the T27A mutant of human alpha defensin HNP4. | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| P12838 | AlphaFold monomer V2.0 prediction for neutrophil defensin 4 (P12838) | predicted | A | — | — |
Ligands
- SO4 · Sulfate ion · in 1 record
Experiment against prediction
- 6DMQ chain H against the predicted model P12838: TM-score 0.92, RMSD 0.41 Å
- 6DMQ chain H against the predicted model P12838: TM-score 0.92, RMSD 0.41 Å
- 6DMQ chain E against the predicted model P12838: TM-score 0.91, RMSD 0.46 Å
- 6DMQ chain E against the predicted model P12838: TM-score 0.91, RMSD 0.46 Å
- 6DMQ chain B against the predicted model P12838: TM-score 0.90, RMSD 0.61 Å
- 6DMQ chain B against the predicted model P12838: TM-score 0.90, RMSD 0.61 Å
- 6DMQ chain F against the predicted model P12838: TM-score 0.90, RMSD 0.66 Å
- 6DMQ chain F against the predicted model P12838: TM-score 0.90, RMSD 0.66 Å
- 1ZMM chain A against the predicted model P12838: TM-score 0.89, RMSD 0.50 Å
- 1ZMM chain A against the predicted model P12838: TM-score 0.89, RMSD 0.50 Å
Elsewhere
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