UniProt P12754
Translation initiation factor eIF-2B subunit delta (P12754)
Translation initiation factor eIF-2B subunit delta (UniProt P12754): 9 experimental structures and 1 predicted model on GenesisL1, 12 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P12754
- Protein
- Translation initiation factor eIF-2B subunit delta
- Experimental structures
- 9
- Predicted models
- 1
- Pockets
- 12 · 1 record with a druggable one
Structures
10 records of P12754 in the MolNFT archive: 9 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6I3M | EIF2B:EIF2 complex, phosphorylated on EIF2 alpha serine 52. | electron microscopy | C, D | — | — |
| 6I7T | EIF2B:EIF2 complex | electron microscopy | C, D | — | — |
| 6QG0 | Structure of EIF2B-EIF2 (phosphorylated at SER51) complex (model 1) | electron microscopy | G, H | — | — |
| 6QG1 | Structure of eIF2B-eIF2 (phosphorylated at Ser51) complex (model 2) | electron microscopy | G, H | — | 12 (best 0.87) |
| 6QG1 | Structure of EIF2B-EIF2 (phosphorylated at SER51) complex (model 2) | electron microscopy | G, H | — | — |
| 6QG2 | Structure of EIF2B-EIF2 (phosphorylated at SER51) complex (model a) | electron microscopy | G, H | — | — |
| 6QG3 | Structure of EIF2B-EIF2 (phosphorylated at SER51) complex (model B) | electron microscopy | G, H | — | — |
| 6QG5 | Structure of EIF2B-EIF2 (phosphorylated at SER51) complex (model C) | electron microscopy | G, H | — | — |
| 6QG6 | Structure of EIF2B-EIF2 (phosphorylated at SER51) complex (model D) | electron microscopy | G, H | — | — |
| P12754 | AlphaFold monomer V2.0 prediction for translation initiation factor eif-2B subunit delta (P12754) | predicted | A | — | — |
Experiment against prediction
- 6I3M chain D against the predicted model P12754: TM-score 0.95, RMSD 1.86 Å
- 6I3M chain C against the predicted model P12754: TM-score 0.95, RMSD 1.86 Å
- 6I7T chain D against the predicted model P12754: TM-score 0.94, RMSD 1.82 Å
- 6I7T chain C against the predicted model P12754: TM-score 0.94, RMSD 1.82 Å
- 6QG1 chain H against the predicted model P12754: TM-score 0.92, RMSD 1.89 Å
- 6QG1 chain H against the predicted model P12754: TM-score 0.92, RMSD 1.89 Å
- 6QG0 chain H against the predicted model P12754: TM-score 0.92, RMSD 1.89 Å
- 6QG1 chain G against the predicted model P12754: TM-score 0.92, RMSD 1.89 Å
- 6QG1 chain G against the predicted model P12754: TM-score 0.92, RMSD 1.89 Å
- 6QG0 chain G against the predicted model P12754: TM-score 0.92, RMSD 1.89 Å
Elsewhere
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