UniProt P12456
Tubulin beta-1 chain (P12456)
Tubulin beta-1 chain (UniProt P12456): 2 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 25 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P12456
- Protein
- Tubulin beta-1 chain
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 25 · 3 records with a druggable one
Structures
3 records of P12456 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8YAJ | ATAT-2 bound MEC-12/MEC-7 microtubule without acetyl-CoA | electron microscopy | D, F | G2P | 9 (best 0.87) |
| 8YAL | ATAT-2 bound K40Q MEC-12/MEC-7 microtubule | electron microscopy | D, F | G2P | 12 (best 0.85) |
| P12456 | AlphaFold monomer V2.0 prediction for tubulin beta-1 chain (P12456) | predicted | A | — | 4 (best 0.59) |
Ligands
- G2P · Phosphomethylphosphonic acid guanylate ester · in 2 records
Experiment against prediction
- 8YAL chain F against the predicted model P12456: TM-score 0.98, RMSD 1.12 Å
- 8YAJ chain F against the predicted model P12456: TM-score 0.98, RMSD 1.13 Å
- 8YAJ chain D against the predicted model P12456: TM-score 0.98, RMSD 1.15 Å
- 8YAL chain D against the predicted model P12456: TM-score 0.98, RMSD 1.16 Å
Elsewhere
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