UniProt P12371
High affinity immunoglobulin epsilon receptor subunit alpha (P12371)
High affinity immunoglobulin epsilon receptor subunit alpha (UniProt P12371): 3 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 17 pockets. Binding sites, druggability and experiment against…
- UniProt
- P12371
- Protein
- High affinity immunoglobulin epsilon receptor subunit alpha
- Experimental structures
- 3
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 17 · 3 records with a druggable one
Structures
4 records of P12371 in the MolNFT archive: 3 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8Y81 | Structure of the ige-fc bound to its high affinity receptor fc(epsilon)ri | electron microscopy | A | NAG, Y01 | 7 (best 0.62) |
| 8ZGS | Structure of the ige-fc bound to its high affinity receptor fc(epsilon)ri state2 | electron microscopy | A | NAG, Y01 | 4 (best 0.71) |
| 8ZGT | Structure of the ige-fc bound to its high affinity receptor fc(epsilon)ri state3 | electron microscopy | A | NAG, Y01 | 6 (best 0.64) |
| P12371 | AlphaFold monomer V2.0 prediction for high affinity immunoglobulin epsilon receptor subunit alpha… | predicted | A | — | — |
Ligands
Experiment against prediction
- 8ZGS chain A against the predicted model P12371: TM-score 0.77, RMSD 2.03 Å
- 8Y81 chain A against the predicted model P12371: TM-score 0.77, RMSD 1.81 Å
- 8ZGT chain A against the predicted model P12371: TM-score 0.76, RMSD 2.08 Å
Elsewhere
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