UniProt P12277
Creatine kinase B-type (P12277)
Creatine kinase B-type (UniProt P12277), EC 2.7.3.2: 9 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 12 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P12277
- Protein
- Creatine kinase B-type
- EC
- 2.7.3.2
- Experimental structures
- 9
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 12 · 2 records with a druggable one
Structures
10 records of P12277 in the MolNFT archive: 9 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3B6R | Crystal structure of Human Brain-type Creatine Kinase | x-ray diffraction | A, B | — | — |
| 3B6R | Crystal structure of human brain-type creatine kinase | x-ray diffraction | A, B | — | — |
| 3DRB | Crystal structure of Human Brain-type Creatine Kinase | x-ray diffraction | A, B | — | — |
| 3DRB | Crystal structure of human brain-type creatine kinase | x-ray diffraction | A, B | — | — |
| 3DRE | Crystal structure of Human Brain-type Creatine Kinase | x-ray diffraction | A, B | — | — |
| 3DRE | Crystal structure of human brain-type creatine kinase | x-ray diffraction | A, B | — | — |
| 6V9H | Ankyrin repeat and SOCS-box protein 9 (ASB9), ElonginB (ELOB), and ElonginC (ELOC) bound to its… | electron microscopy | A, B | — | 6 (best 0.84) |
| 6V9H | Ankyrin repeat and socs-box protein 9 (ASB9), elonginb (elob), and elonginc (eloc) bound to its… | electron microscopy | A, B | — | — |
| 7TUN | Crystal structure analysis of human CKB complex with a covalent compound | x-ray diffraction | A, B | KLU | 6 (best 0.84) |
| P12277 | AlphaFold monomer V2.0 prediction for creatine kinase B-type (P12277) | predicted | A | — | — |
Ligands
- KLU · (2S)-4-(chloroacetyl)-3,4-dihydro-2H-1,4-benzoxazine-2-carboxamide · in 1 record
Experiment against prediction
- 7TUN chain B against the predicted model P12277: TM-score 0.99, RMSD 0.88 Å
- 6V9H chain B against the predicted model P12277: TM-score 0.98, RMSD 1.00 Å
- 6V9H chain B against the predicted model P12277: TM-score 0.98, RMSD 1.00 Å
- 3DRE chain B against the predicted model P12277: TM-score 0.98, RMSD 0.99 Å
- 3DRE chain B against the predicted model P12277: TM-score 0.98, RMSD 0.99 Å
- 6V9H chain A against the predicted model P12277: TM-score 0.98, RMSD 1.01 Å
- 6V9H chain A against the predicted model P12277: TM-score 0.98, RMSD 1.01 Å
- 7TUN chain A against the predicted model P12277: TM-score 0.97, RMSD 1.36 Å
- 3B6R chain A against the predicted model P12277: TM-score 0.97, RMSD 1.35 Å
- 3B6R chain A against the predicted model P12277: TM-score 0.97, RMSD 1.35 Å
Elsewhere
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