UniProt P11978
Regulatory protein SIR4 (P11978)
Regulatory protein SIR4 (UniProt P11978): 14 experimental structures on GenesisL1, 3 ligands bound, 14 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P11978
- Protein
- Regulatory protein SIR4
- Experimental structures
- 14
- Predicted models
- 0
- Ligands
- 3
- Pockets
- 14 · 1 record with a druggable one
Structures
14 records of P11978 in the MolNFT archive: 14 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1NYH | Crystal Structure of the Coiled-coil Dimerization Motif of Sir4 | x-ray diffraction | A | — | — |
| 1NYH | Crystal structure of the coiled-coil dimerization motif of SIR4 | x-ray diffraction | A | — | — |
| 1PL5 | Crystal Structure Analysis of the Sir4p C-terminal Coiled Coil | x-ray diffraction | A, S | — | — |
| 1PL5 | Crystal structure analysis of the SIR4P C-terminal coiled coil | x-ray diffraction | A, S | — | — |
| 4IAO | Crystal structure of Sir2 C543S mutant in complex with SID domain of Sir4 | x-ray diffraction | C, D | — | — |
| 4IAO | Crystal structure of SIR2 C543S mutant in complex with sid domain of SIR4 | x-ray diffraction | C, D | — | — |
| 6QSZ | Crystal structure of the SIR4 H-brct domain in complex with ESC1 PS1450 peptide | x-ray diffraction | A, C, E, G, I, K, M, O | CL | — |
| 6QTM | Crystal structure of the Sir4 H-BRCT domain in complex with Ty5 pS1095 peptide | x-ray diffraction | A, B, C | SO4 | — |
| 6QTM | Crystal structure of the SIR4 H-brct domain in complex with TY5 PS1095 peptide | x-ray diffraction | A, B, C | SO4 | — |
| 6RR0 | Crystal structure of the Sir4 H-BRCT domain in complex with Ubp10 pT123 peptide | x-ray diffraction | A, B, C, D, E, F, G | CL | 14 (best 0.68) |
| 6RR0 | Crystal structure of the SIR4 H-brct domain in complex with UBP10 PT123 peptide | x-ray diffraction | A, B, C, D, E, F, G | CL | — |
| 6RRV | Crystal structure of the Sir4 H-BRCT domain | x-ray diffraction | A | CL, BR | — |
| 6RRV | Crystal structure of the SIR4 H-brct domain | x-ray diffraction | A | CL, BR | — |
| P11978 | AlphaFold monomer V2.0 prediction for regulatory protein SIR4 (P11978) | — | — | — |
Ligands
Elsewhere
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