UniProt P11908
Ribose-phosphate pyrophosphokinase 2 (P11908)
Ribose-phosphate pyrophosphokinase 2 (UniProt P11908), EC 2.7.6.1: 1 experimental structure and 1 predicted model on GenesisL1, 3 ligands bound, 23 pockets. Binding sites, druggability and experiment against prediction (TM-score)…
- UniProt
- P11908
- Protein
- Ribose-phosphate pyrophosphokinase 2
- EC
- 2.7.6.1
- Experimental structures
- 1
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 23 · 1 record with a druggable one
Structures
2 records of P11908 in the MolNFT archive: 1 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7YK1 | Structural basis of human PRPS2 filaments | electron microscopy | A, B, C, D, E, F | PO4, MG, ADP | 20 (best 0.77) |
| P11908 | AlphaFold monomer V2.0 prediction for ribose-phosphate pyrophosphokinase 2 (P11908) | predicted | A | — | 3 (best 0.49) |
Ligands
Experiment against prediction
- 7YK1 chain F against the predicted model P11908: TM-score 0.99, RMSD 0.69 Å
- 7YK1 chain B against the predicted model P11908: TM-score 0.99, RMSD 0.69 Å
- 7YK1 chain E against the predicted model P11908: TM-score 0.99, RMSD 0.69 Å
- 7YK1 chain C against the predicted model P11908: TM-score 0.99, RMSD 0.69 Å
- 7YK1 chain A against the predicted model P11908: TM-score 0.99, RMSD 0.69 Å
- 7YK1 chain D against the predicted model P11908: TM-score 0.99, RMSD 0.70 Å
Elsewhere
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