UniProt P11835
Integrin beta-2,Talin-1 (P11835)
Integrin beta-2,Talin-1 (UniProt P11835): 3 experimental structures and 1 predicted model on GenesisL1, 12 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P11835
- Protein
- Integrin beta-2,Talin-1
- Experimental structures
- 3
- Predicted models
- 1
- Pockets
- 12 · 3 records with a druggable one
Structures
4 records of P11835 in the MolNFT archive: 3 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8FSE | Crystal structure of integrin beta-2 tail bound to the FERM-folded talin head domain | x-ray diffraction | A, B | — | 7 (best 0.70) |
| 8T0A | Crystal structure of integrin beta-2 tail bound to the FERM-folded talin head domain with a Y270E… | x-ray diffraction | A | — | 2 (best 0.71) |
| 8T0D | Crystal structure of integrin beta-2 tail bound to the FERM-folded talin head domain with… | x-ray diffraction | A | — | 3 (best 0.62) |
| P11835 | AlphaFold monomer V2.0 prediction for integrin beta-2 (P11835) | predicted | A | — | — |
Experiment against prediction
- 8T0D chain A against the predicted model P11835: TM-score 0.27, RMSD 6.76 Å
- 8T0A chain A against the predicted model P11835: TM-score 0.26, RMSD 6.38 Å
- 8FSE chain A against the predicted model P11835: TM-score 0.26, RMSD 6.72 Å
- 8FSE chain B against the predicted model P11835: TM-score 0.25, RMSD 6.41 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.