UniProt P11802
Cyclin-dependent kinase 4 (P11802)
Cyclin-dependent kinase 4 (UniProt P11802): 24 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 13 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P11802
- Protein
- Cyclin-dependent kinase 4
- Experimental structures
- 24
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 13 · 2 records with a druggable one
Structures
25 records of P11802 in the MolNFT archive: 24 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2W96 | Crystal Structure of CDK4 in complex with a D-type cyclin | x-ray diffraction | B | — | — |
| 2W96 | Crystal structure of CDK4 in complex with a D-type cyclin | x-ray diffraction | B | — | — |
| 2W99 | Crystal Structure of CDK4 in complex with a D-type cyclin | x-ray diffraction | B | — | — |
| 2W99 | Crystal structure of CDK4 in complex with a D-type cyclin | x-ray diffraction | B | — | — |
| 2W9F | Crystal Structure of CDK4 in complex with a D-type cyclin | x-ray diffraction | B | — | — |
| 2W9F | Crystal structure of CDK4 in complex with a D-type cyclin | x-ray diffraction | B | — | — |
| 2W9Z | Crystal Structure of CDK4 in complex with a D-type cyclin | x-ray diffraction | B | — | — |
| 2W9Z | Crystal structure of CDK4 in complex with a D-type cyclin | x-ray diffraction | B | — | — |
| 3G33 | Crystal structure of CDK4/cyclin D3 | x-ray diffraction | A, C | — | — |
| 3G33 | Crystal structure of CDK4/CYCLIN D3 | x-ray diffraction | A, C | — | — |
| 5FWK | Atomic cryoEM structure of Hsp90-Cdc37-Cdk4 complex | electron microscopy | K | — | — |
| 5FWK | Atomic cryoem structure of HSP90-CDC37-CDK4 complex | electron microscopy | K | — | — |
| 5FWL | Atomic cryoEM structure of Hsp90-Cdc37-Cdk4 complex | electron microscopy | K | — | — |
| 5FWL | Atomic cryoem structure of HSP90-CDC37-CDK4 complex | electron microscopy | K | — | — |
| 5FWM | Atomic cryoEM structure of Hsp90-Cdc37-Cdk4 complex | electron microscopy | K | — | 8 (best 0.83) |
| 5FWM | Atomic cryoem structure of HSP90-CDC37-CDK4 complex | electron microscopy | K | — | — |
| 5FWP | Atomic cryoEM structure of Hsp90-Cdc37-Cdk4 complex | electron microscopy | K | — | 5 (best 0.83) |
| 5FWP | Atomic cryoem structure of HSP90-CDC37-CDK4 complex | electron microscopy | K | — | — |
| 6P8E | Crystal structure of CDK4 in complex with CYCLIND1 and P27 | x-ray diffraction | B | MG | — |
| 6P8F | Crystal structure of CDK4 in complex with CYCLIND1 and P27 | x-ray diffraction | B | — | — |
| 6P8G | Crystal structure of CDK4 in complex with CyclinD1 and P27 | x-ray diffraction | B | — | — |
| 6P8G | Crystal structure of CDK4 in complex with CYCLIND1 and P27 | x-ray diffraction | B | — | — |
| 6P8H | Crystal structure of CDK4 in complex with CyclinD1 and P21 | x-ray diffraction | B | — | — |
| 6P8H | Crystal structure of CDK4 in complex with CYCLIND1 and P21 | x-ray diffraction | B | — | — |
| P11802 | AlphaFold monomer V2.0 prediction for cyclin-dependent kinase 4 (P11802) | predicted | A | — | — |
Ligands
- MG · Magnesium ion · in 1 record
Experiment against prediction
- 3G33 chain C against the predicted model P11802: TM-score 0.97, RMSD 1.11 Å
- 3G33 chain C against the predicted model P11802: TM-score 0.97, RMSD 1.11 Å
- 3G33 chain A against the predicted model P11802: TM-score 0.97, RMSD 1.20 Å
- 3G33 chain A against the predicted model P11802: TM-score 0.97, RMSD 1.20 Å
- 2W9F chain B against the predicted model P11802: TM-score 0.96, RMSD 1.26 Å
- 2W9F chain B against the predicted model P11802: TM-score 0.96, RMSD 1.26 Å
- 2W96 chain B against the predicted model P11802: TM-score 0.96, RMSD 1.31 Å
- 2W96 chain B against the predicted model P11802: TM-score 0.96, RMSD 1.31 Å
- 2W9Z chain B against the predicted model P11802: TM-score 0.96, RMSD 1.45 Å
- 2W9Z chain B against the predicted model P11802: TM-score 0.96, RMSD 1.45 Å
Elsewhere
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