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UniProt P11766

Alcohol dehydrogenase class-3 (P11766)

Alcohol dehydrogenase class-3 (UniProt P11766), EC 1.1.1.-, 1.1.1.1: 19 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 3 pockets. Binding sites, druggability and experiment against prediction…

UniProt
P11766
Protein
Alcohol dehydrogenase class-3
EC
1.1.1.-, 1.1.1.1, 1.1.1.284
Experimental structures
19
Predicted models
1
Ligands
3
Pockets
3 · 1 record with a druggable one

Structures

20 records of P11766 in the MolNFT archive: 19 experimental, 1 predicted.

EntryTitleMethodChainsLigandsPockets
1M6HHuman glutathione-dependent formaldehyde dehydrogenasex-ray diffractionA, B——
1M6HHuman glutathione-dependent formaldehyde dehydrogenasex-ray diffractionA, B——
1M6WBinary complex of Human glutathione-dependent formaldehyde dehydrogenase and 12-Hydroxydodecanoic…x-ray diffractionA, B——
1M6WBinary complex of human glutathione-dependent formaldehyde dehydrogenase and 12-hydroxydodecanoic…x-ray diffractionA, B——
1MA0Ternary complex of Human glutathione-dependent formaldehyde dehydrogenase with NAD+ and dodecanoic…x-ray diffractionA, B——
1MA0Ternary complex of human glutathione-dependent formaldehyde dehydrogenase with NAD+ and dodecanoic…x-ray diffractionA, B——
1MC5Ternary complex of Human glutathione-dependent formaldehyde dehydrogenase with…x-ray diffractionA, B——
1MC5Ternary complex of human glutathione-dependent formaldehyde dehydrogenase with…x-ray diffractionA, B——
1MP0Binary Complex of Human Glutathione-Dependent Formaldehyde Dehydrogenase with NAD(H)x-ray diffractionA, B——
1MP0Binary complex of human glutathione-dependent formaldehyde dehydrogenase with NAD(H)x-ray diffractionA, B——
1TEHStructure of human liver chichi alcohol dehydrogenase (a glutathione-dependent formaldehyde…x-ray diffractionA, B——
1TEHStructure of human liver chichi alcohol dehydrogenase (a glutathione- dependent formaldehyde…x-ray diffractionA, B——
2FZECrystal structure of the binary complex of human glutathione-dependent formaldehyde dehydrogenase…x-ray diffractionA, B——
2FZECrystal structure of the binary complex of human glutathione-dependent formaldehyde dehydrogenase…x-ray diffractionA, B——
2FZWStructure of the binary complex of the E67L mutant of human glutathione-dependent formaldehyde…x-ray diffractionA, B——
2FZWStructure of the binary complex of the E67L mutant of human glutathione-dependent formaldehyde…x-ray diffractionA, B——
3QJ5S-nitrosoglutathione reductase (GSNOR) in complex with N6022x-ray diffractionA, B——
3QJ5S-nitrosoglutathione reductase (gsnor) in complex with N6022x-ray diffractionA, B——
8GV3The cryo-EM structure of GSNOR with NYY001electron microscopyA, BZN, NAD, WKZ3 (best 0.79)
P11766AlphaFold monomer V2.0 prediction for alcohol dehydrogenase class-3 (P11766)predictedA——

Ligands

  • NAD · Nicotinamide-adenine-dinucleotide · in 1 record
  • WKZ · (4P)-4-{2-[4-(1H-imidazol-1-yl)phenyl]-5-[3-oxo-3-(2-oxo-1,3-thiazolidin-3-yl)propyl]-1H-pyrrol-1-yl}-3-methylbenzamide · in 1 record
  • ZN · Zinc ion · in 1 record

Experiment against prediction

Elsewhere

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