UniProt P11766
Alcohol dehydrogenase class-3 (P11766)
Alcohol dehydrogenase class-3 (UniProt P11766), EC 1.1.1.-, 1.1.1.1: 19 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 3 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- P11766
- Protein
- Alcohol dehydrogenase class-3
- EC
- 1.1.1.-, 1.1.1.1, 1.1.1.284
- Experimental structures
- 19
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 3 · 1 record with a druggable one
Structures
20 records of P11766 in the MolNFT archive: 19 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1M6H | Human glutathione-dependent formaldehyde dehydrogenase | x-ray diffraction | A, B | — | — |
| 1M6H | Human glutathione-dependent formaldehyde dehydrogenase | x-ray diffraction | A, B | — | — |
| 1M6W | Binary complex of Human glutathione-dependent formaldehyde dehydrogenase and 12-Hydroxydodecanoic… | x-ray diffraction | A, B | — | — |
| 1M6W | Binary complex of human glutathione-dependent formaldehyde dehydrogenase and 12-hydroxydodecanoic… | x-ray diffraction | A, B | — | — |
| 1MA0 | Ternary complex of Human glutathione-dependent formaldehyde dehydrogenase with NAD+ and dodecanoic… | x-ray diffraction | A, B | — | — |
| 1MA0 | Ternary complex of human glutathione-dependent formaldehyde dehydrogenase with NAD+ and dodecanoic… | x-ray diffraction | A, B | — | — |
| 1MC5 | Ternary complex of Human glutathione-dependent formaldehyde dehydrogenase with… | x-ray diffraction | A, B | — | — |
| 1MC5 | Ternary complex of human glutathione-dependent formaldehyde dehydrogenase with… | x-ray diffraction | A, B | — | — |
| 1MP0 | Binary Complex of Human Glutathione-Dependent Formaldehyde Dehydrogenase with NAD(H) | x-ray diffraction | A, B | — | — |
| 1MP0 | Binary complex of human glutathione-dependent formaldehyde dehydrogenase with NAD(H) | x-ray diffraction | A, B | — | — |
| 1TEH | Structure of human liver chichi alcohol dehydrogenase (a glutathione-dependent formaldehyde… | x-ray diffraction | A, B | — | — |
| 1TEH | Structure of human liver chichi alcohol dehydrogenase (a glutathione- dependent formaldehyde… | x-ray diffraction | A, B | — | — |
| 2FZE | Crystal structure of the binary complex of human glutathione-dependent formaldehyde dehydrogenase… | x-ray diffraction | A, B | — | — |
| 2FZE | Crystal structure of the binary complex of human glutathione-dependent formaldehyde dehydrogenase… | x-ray diffraction | A, B | — | — |
| 2FZW | Structure of the binary complex of the E67L mutant of human glutathione-dependent formaldehyde… | x-ray diffraction | A, B | — | — |
| 2FZW | Structure of the binary complex of the E67L mutant of human glutathione-dependent formaldehyde… | x-ray diffraction | A, B | — | — |
| 3QJ5 | S-nitrosoglutathione reductase (GSNOR) in complex with N6022 | x-ray diffraction | A, B | — | — |
| 3QJ5 | S-nitrosoglutathione reductase (gsnor) in complex with N6022 | x-ray diffraction | A, B | — | — |
| 8GV3 | The cryo-EM structure of GSNOR with NYY001 | electron microscopy | A, B | ZN, NAD, WKZ | 3 (best 0.79) |
| P11766 | AlphaFold monomer V2.0 prediction for alcohol dehydrogenase class-3 (P11766) | predicted | A | — | — |
Ligands
Experiment against prediction
- 2FZE chain A against the predicted model P11766: TM-score 1.00, RMSD 0.24 Å
- 2FZE chain A against the predicted model P11766: TM-score 1.00, RMSD 0.24 Å
- 3QJ5 chain A against the predicted model P11766: TM-score 1.00, RMSD 0.26 Å
- 3QJ5 chain A against the predicted model P11766: TM-score 1.00, RMSD 0.26 Å
- 2FZW chain A against the predicted model P11766: TM-score 1.00, RMSD 0.26 Å
- 2FZW chain A against the predicted model P11766: TM-score 1.00, RMSD 0.26 Å
- 1MA0 chain A against the predicted model P11766: TM-score 1.00, RMSD 0.27 Å
- 1MA0 chain A against the predicted model P11766: TM-score 1.00, RMSD 0.27 Å
- 1M6H chain B against the predicted model P11766: TM-score 1.00, RMSD 0.28 Å
- 1M6H chain B against the predicted model P11766: TM-score 1.00, RMSD 0.28 Å
Elsewhere
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