UniProt P11511
P11511
P11511 (UniProt P11511): 22 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P11511
- Experimental structures
- 22
- Predicted models
- 1
- Ligands
- 4
Structures
23 records of P11511 in the MolNFT archive: 22 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3EQM | Crystal structure of human placental aromatase cytochrome P450 in complex with androstenedione | x-ray diffraction | A | — | — |
| 3EQM | Crystal structure of human placental aromatase cytochrome P450 in complex with androstenedione | x-ray diffraction | A | — | — |
| 3S79 | Human placental aromatase cytochrome P450 (CYP19A1) refined at 2.75 angstrom | x-ray diffraction | A | — | — |
| 3S79 | Human placental aromatase cytochrome P450 (CYP19A1) refined at 2.75 ångström | x-ray diffraction | A | — | — |
| 3S7S | Crystal structure of human placental aromatase complexed with breast cancer drug exemestane | x-ray diffraction | A | — | — |
| 3S7S | Crystal structure of human placental aromatase complexed with breast cancer drug exemestane | x-ray diffraction | A | — | — |
| 4GL5 | Structure of human placental aromatase complexed with designed inhibitor HDDG029 (compound 4) | x-ray diffraction | A | — | — |
| 4GL5 | Structure of human placental aromatase complexed with designed inhibitor HDDG029 (compound 4) | x-ray diffraction | A | — | — |
| 4GL7 | Structure of human placental aromatase complexed with designed inhibitor HDDG046 (compound 5) | x-ray diffraction | A | — | — |
| 4GL7 | Structure of human placental aromatase complexed with designed inhibitor HDDG046 (compound 5) | x-ray diffraction | A | — | — |
| 4KQ8 | Structure of Recombinant Human Cytochrome P450 Aromatase | x-ray diffraction | A | — | — |
| 4KQ8 | Structure of recombinant human cytochrome P450 aromatase | x-ray diffraction | A | — | — |
| 5JKV | Human placental aromatase cytochrome P450 (CYP19A1) at 2.75 ångström with bound polyethylene glycol | x-ray diffraction | A | HEM, ASD, PO4 | — |
| 5JKV | Human placental aromatase cytochrome P450 (CYP19A1) at 2.75 ångström with bound polyethylene glycol | x-ray diffraction | A | — | — |
| 5JKW | Human placental aromatase cytochrome P450 (CYP19A1) complexed with testosterone | x-ray diffraction | A | HEM, TES | — |
| 5JKW | Human placental aromatase cytochrome P450 (CYP19A1) complexed with testosterone | x-ray diffraction | A | — | — |
| 5JL6 | Human placental aromatase cytochrome P450 (CYP19A1): androstenedione complex #2 | x-ray diffraction | A | HEM, ASD | — |
| 5JL6 | Human placental aromatase cytochrome P450 (CYP19A1): androstenedione complex #2 | x-ray diffraction | A | — | — |
| 5JL7 | Human placental aromatase cytochrome P450 (CYP19A1): androstenedione complex #3 | x-ray diffraction | A | HEM, ASD | — |
| 5JL7 | Human placental aromatase cytochrome P450 (CYP19A1): androstenedione complex #3 | x-ray diffraction | A | — | — |
| 5JL9 | Human placental aromatase cytochrome P450 (CYP19A1): androstenedione complex #4 | x-ray diffraction | A | HEM, ASD | — |
| 5JL9 | Human placental aromatase cytochrome P450 (CYP19A1): androstenedione complex #4 | x-ray diffraction | A | — | — |
| P11511 | AlphaFold monomer V2.0 prediction for aromatase (P11511) | predicted | A | — | — |
Ligands
Experiment against prediction
- 5JKV chain A against the predicted model P11511: TM-score 1.00, RMSD 0.49 Å
- 5JKV chain A against the predicted model P11511: TM-score 1.00, RMSD 0.49 Å
- 5JL9 chain A against the predicted model P11511: TM-score 1.00, RMSD 0.49 Å
- 5JL9 chain A against the predicted model P11511: TM-score 1.00, RMSD 0.49 Å
- 3S79 chain A against the predicted model P11511: TM-score 1.00, RMSD 0.50 Å
- 3S79 chain A against the predicted model P11511: TM-score 1.00, RMSD 0.50 Å
- 5JKW chain A against the predicted model P11511: TM-score 1.00, RMSD 0.50 Å
- 5JKW chain A against the predicted model P11511: TM-score 1.00, RMSD 0.50 Å
- 5JL7 chain A against the predicted model P11511: TM-score 1.00, RMSD 0.50 Å
- 5JL7 chain A against the predicted model P11511: TM-score 1.00, RMSD 0.50 Å
Elsewhere
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