UniProt P11308
P11308
P11308 (UniProt P11308): 14 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P11308
- Experimental structures
- 14
- Predicted models
- 1
- Ligands
- 1
Structures
15 records of P11308 in the MolNFT archive: 14 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1SXE | The solution structure of the Pointed (PNT) domain from the transcrition factor Erg | solution nmr | A | — | — |
| 1SXE | The solution structure of the pointed (pnt) domain from the transcrition factor erg | solution nmr | A | — | — |
| 4IRG | Uninhibited DNA-binding domain of the Ets transcription factor ERG | x-ray diffraction | A | — | — |
| 4IRG | Uninhibited DNA-binding domain of the ets transcription factor erg | x-ray diffraction | A | — | — |
| 4IRH | Auto-inhibited ERG Ets domain | x-ray diffraction | A | — | — |
| 4IRH | Auto-inhibited erg ets domain | x-ray diffraction | A | — | — |
| 4IRI | Auto-inhibited ERG Ets Domain-DNA Complex | x-ray diffraction | A | — | — |
| 4IRI | Auto-inhibited erg ets domain-DNA complex | x-ray diffraction | A | — | — |
| 5YBC | X-ray structure of native ets-domain domain of ERGP55 | x-ray diffraction | C, A | — | — |
| 5YBD | X-ray structure of ETS domain of Ergp55 in complex with E74DNA | x-ray diffraction | A, X | — | — |
| 5YBD | X-ray structure of ets domain of ERGP55 in complex with E74DNA | x-ray diffraction | A, X | — | — |
| 6VGE | Crystal structure of the DNA binding domains of human transcription factor erg, human RUNX2 bound… | x-ray diffraction | A | — | — |
| 6VGG | Crystal structure of the DNA binding domains of human transcription factor ERG, human Runx2 bound… | x-ray diffraction | A | QWP | — |
| 6VGG | Crystal structure of the DNA binding domains of human transcription factor erg, human RUNX2 bound… | x-ray diffraction | A | QWP | — |
| P11308 | AlphaFold monomer V2.0 prediction for transcriptional regulator erg (P11308) | predicted | A | — | — |
Ligands
- QWP · mithramycin · in 2 records
Experiment against prediction
- 4IRI chain A against the predicted model P11308: TM-score 0.98, RMSD 0.57 Å
- 4IRI chain A against the predicted model P11308: TM-score 0.98, RMSD 0.57 Å
- 4IRG chain A against the predicted model P11308: TM-score 0.95, RMSD 0.95 Å
- 4IRG chain A against the predicted model P11308: TM-score 0.95, RMSD 0.95 Å
- 5YBC chain C against the predicted model P11308: TM-score 0.94, RMSD 1.10 Å
- 5YBC chain A against the predicted model P11308: TM-score 0.92, RMSD 1.25 Å
- 5YBD chain X against the predicted model P11308: TM-score 0.92, RMSD 1.51 Å
- 5YBD chain X against the predicted model P11308: TM-score 0.92, RMSD 1.51 Å
- 4IRH chain A against the predicted model P11308: TM-score 0.92, RMSD 1.04 Å
- 4IRH chain A against the predicted model P11308: TM-score 0.92, RMSD 1.04 Å
Elsewhere
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