UniProt P11275
Venus-tagged CaMKII Alpha Association Domain (P11275)
Venus-tagged CaMKII Alpha Association Domain (UniProt P11275), EC 2.7.11.17: 9 experimental structures and 1 predicted model on GenesisL1, 26 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- P11275
- Protein
- Venus-tagged CaMKII Alpha Association Domain
- EC
- 2.7.11.17
- Experimental structures
- 9
- Predicted models
- 1
- Pockets
- 26 · 2 records with a druggable one
Structures
10 records of P11275 in the MolNFT archive: 9 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1CDM | Modulation of calmodulin plasticity in molecular recognition on the basis of X-ray structures | x-ray diffraction | B | — | — |
| 1CDM | Modulation of calmodulin plasticity in molecular recognition on the basis of X-ray structures | x-ray diffraction | B | — | — |
| 1CM1 | Motions of calmodulin-single-conformer refinement | x-ray diffraction | B | — | — |
| 1CM1 | Motions of calmodulin-single-conformer refinement | x-ray diffraction | B | — | — |
| 1CM4 | Motions of calmodulin-four-conformer refinement | x-ray diffraction | B | — | — |
| 1CM4 | Motions of calmodulin-four-conformer refinement | x-ray diffraction | B | — | — |
| 5U6Y | Pseudo-atomic model of the CaMKIIa holoenzyme. | electron microscopy | A, B, C, D, E, F, G, H, I, J, K, L | — | — |
| 5U6Y | Pseudo-atomic model of the camkiia holoenzyme. | electron microscopy | A, B, C, D, E, F, G, H, I, J, K, L | — | — |
| 8SYG | Cryo-EM structure of tetradecameric hub domain of CaMKII alpha | electron microscopy | B, A, C, D, E, F, G, H, I, J, K, L, M, N | — | 20 (best 0.73) |
| P11275 | AlphaFold monomer V2.0 prediction for CALCIUM/CALMODULIN-dependent protein kinase type II subunit… | predicted | A | — | 6 (best 0.79) |
Experiment against prediction
- 8SYG chain B against the predicted model P11275: TM-score 0.97, RMSD 0.77 Å
- 1CDM chain B against the predicted model P11275: TM-score 0.70, RMSD 1.30 Å
- 1CDM chain B against the predicted model P11275: TM-score 0.70, RMSD 1.30 Å
- 1CM1 chain B against the predicted model P11275: TM-score 0.69, RMSD 1.30 Å
- 1CM1 chain B against the predicted model P11275: TM-score 0.69, RMSD 1.30 Å
- 1CM4 chain B against the predicted model P11275: TM-score 0.68, RMSD 0.37 Å
- 1CM4 chain B against the predicted model P11275: TM-score 0.68, RMSD 0.37 Å
- 5U6Y chain A against the predicted model P11275: TM-score 0.63, RMSD 1.51 Å
- 5U6Y chain A against the predicted model P11275: TM-score 0.63, RMSD 1.51 Å
- 8SYG chain J against the predicted model P42212: TM-score 0.38, RMSD 4.84 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.