UniProt P11179
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial (P11179)
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial (UniProt P11179), EC 2.3.1.61: 1 experimental structure and 1 predicted model on GenesisL1, 24 pockets. Binding…
- UniProt
- P11179
- Protein
- Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate…
- EC
- 2.3.1.61
- Experimental structures
- 1
- Predicted models
- 1
- Pockets
- 24 · 2 records with a druggable one
Structures
2 records of P11179 in the MolNFT archive: 1 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7UOL | Endogenous dihydrolipoamide succinyltransferase (E2) core of 2-oxoglutarate dehydrogenase complex… | electron microscopy | D, E, F, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X, Y, Z, a, b, c, d | — | 20 (best 0.86) |
| P11179 | AlphaFold monomer V2.0 prediction for dihydrolipoyllysine-residue succinyltransferase component of… | predicted | A | — | 4 (best 0.69) |
Experiment against prediction
- 7UOL chain E against the predicted model P11179: TM-score 0.98, RMSD 0.91 Å
- 7UOL chain F against the predicted model P11179: TM-score 0.98, RMSD 0.91 Å
- 7UOL chain U against the predicted model P11179: TM-score 0.98, RMSD 0.91 Å
- 7UOL chain Y against the predicted model P11179: TM-score 0.98, RMSD 0.91 Å
- 7UOL chain d against the predicted model P11179: TM-score 0.98, RMSD 0.91 Å
- 7UOL chain D against the predicted model P11179: TM-score 0.98, RMSD 0.91 Å
- 7UOL chain P against the predicted model P11179: TM-score 0.98, RMSD 0.91 Å
- 7UOL chain b against the predicted model P11179: TM-score 0.98, RMSD 0.91 Å
- 7UOL chain L against the predicted model P11179: TM-score 0.98, RMSD 0.91 Å
- 7UOL chain S against the predicted model P11179: TM-score 0.98, RMSD 0.91 Å
Elsewhere
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