UniProt P11169
Solute carrier family 2, facilitated glucose transporter member 3 (P11169)
Solute carrier family 2, facilitated glucose transporter member 3 (UniProt P11169): 12 experimental structures and 1 predicted model on GenesisL1, 5 ligands bound, 14 pockets. Binding sites, druggability and experiment against…
- UniProt
- P11169
- Protein
- Solute carrier family 2, facilitated glucose transporter member 3
- Experimental structures
- 12
- Predicted models
- 1
- Ligands
- 5
- Pockets
- 14 · 2 records with a druggable one
Structures
13 records of P11169 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4ZW9 | Crystal structure of human GLUT3 bound to D-glucose in the outward-occluded conformation at 1.5… | x-ray diffraction | A | — | — |
| 4ZW9 | Crystal structure of human GLUT3 bound to D-glucose in the outward- occluded conformation at 1.5… | x-ray diffraction | A | — | — |
| 4ZWB | Crystal structure of maltose-bound human GLUT3 in the outward-occluded conformation at 2.4 angstrom | x-ray diffraction | A | — | — |
| 4ZWB | Crystal structure of maltose-bound human GLUT3 in the outward-occluded conformation at 2.4 ångström | x-ray diffraction | A | — | — |
| 4ZWC | Crystal structure of maltose-bound human GLUT3 in the outward-open conformation at 2.6 angstrom | x-ray diffraction | A, B | — | — |
| 4ZWC | Crystal structure of maltose-bound human GLUT3 in the outward-open conformation at 2.6 ångström | x-ray diffraction | A, B | — | — |
| 5C65 | Structure of the human glucose transporter GLUT3 / SLC2A3 | x-ray diffraction | A, B | 37X, Y01 | 7 (best 0.78) |
| 5C65 | Structure of the human glucose transporter GLUT3 / SLC2A3 | x-ray diffraction | A, B | — | — |
| 7CRZ | Crystal structure of human glucose transporter GLUT3 bound with C3361 | x-ray diffraction | A | F00 | — |
| 7SPS | Crystal structure of human glucose transporter GLUT3 bound with exofacial inhibitor SA47 | x-ray diffraction | A, B | A0E | 7 (best 0.79) |
| 7SPS | Crystal structure of human glucose transporter GLUT3 bound with exofacial inhibitor SA47 | x-ray diffraction | A, B | A0E | — |
| 7SPT | Crystal structure of exofacial state human glucose transporter GLUT3 | x-ray diffraction | A | GLC | — |
| P11169 | AlphaFold monomer V2.0 prediction for solute carrier family 2, facilitated glucose transporter… | predicted | A | — | — |
Ligands
- A0E · methyl N-[(2-{4-[4-(5-fluoro-2-methoxyphenyl)piperazin-1-yl]-1H-pyrazolo[3,4-d]pyrimidin-1-yl}phenyl)methyl]-beta-alaninate · in 2 records
- 37X · Octyl Glucose Neopentyl Glycol · in 1 record
- F00 · (2S,3R,4S,5R,6R)-6-(hydroxymethyl)-4-undec-10-enoxy-oxane-2,3,5-triol · in 1 record
- GLC · alpha-D-glucopyranose · in 1 record
- Y01 · Cholesterol hemisuccinate · in 1 record
Experiment against prediction
- 5C65 chain A against the predicted model P11169: TM-score 0.99, RMSD 0.72 Å
- 5C65 chain A against the predicted model P11169: TM-score 0.99, RMSD 0.72 Å
- 5C65 chain B against the predicted model P11169: TM-score 0.99, RMSD 0.72 Å
- 5C65 chain B against the predicted model P11169: TM-score 0.99, RMSD 0.72 Å
- 7CRZ chain A against the predicted model P11169: TM-score 0.99, RMSD 0.82 Å
- 4ZWB chain A against the predicted model P11169: TM-score 0.99, RMSD 0.87 Å
- 4ZWB chain A against the predicted model P11169: TM-score 0.99, RMSD 0.87 Å
- 7SPT chain A against the predicted model P11169: TM-score 0.99, RMSD 0.95 Å
- 4ZWC chain A against the predicted model P11169: TM-score 0.99, RMSD 0.97 Å
- 4ZWC chain A against the predicted model P11169: TM-score 0.99, RMSD 0.97 Å
Elsewhere
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