UniProt P10643
Complement component C7 (P10643)
Complement component C7 (UniProt P10643): 8 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 17 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P10643
- Protein
- Complement component C7
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 17 · 2 records with a druggable one
Structures
9 records of P10643 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2WCY | NMR solution structure of factor I-like modules of complement C7. | solution nmr | A | — | — |
| 2WCY | NMR solution structure of factor I-like modules of complement C7. | solution nmr | A | — | — |
| 6H03 | Open conformation of the membrane attack complex | electron microscopy | D | NAG | — |
| 6H04 | Closed conformation of the Membrane Attack Complex | electron microscopy | D | NAG | — |
| 6H04 | Closed conformation of the membrane attack complex | electron microscopy | D | NAG | — |
| 7NYC | Cryoem structure of 3C9-smac | electron microscopy | C | NAG, BMA, FUC | — |
| 8B0G | 2C9, C5b9-CD59 structure | electron microscopy | C | NAG | 8 (best 0.86) |
| 8B0H | 2C9, C5b9-CD59 cryoEM structure | electron microscopy | C | — | 9 (best 0.85) |
| P10643 | AlphaFold monomer V2.0 prediction for complement component C7 (P10643) | predicted | A | — | — |
Ligands
Experiment against prediction
- 2WCY chain A against the predicted model P10643: TM-score 0.76, RMSD 2.95 Å
- 2WCY chain A against the predicted model P10643: TM-score 0.76, RMSD 2.95 Å
- 8B0G chain C against the predicted model P10643: TM-score 0.59, RMSD 4.42 Å
- 8B0H chain C against the predicted model P10643: TM-score 0.59, RMSD 4.47 Å
- 6H03 chain D against the predicted model P10643: TM-score 0.56, RMSD 4.58 Å
- 6H04 chain D against the predicted model P10643: TM-score 0.56, RMSD 4.59 Å
- 6H04 chain D against the predicted model P10643: TM-score 0.56, RMSD 4.59 Å
- 7NYC chain C against the predicted model P10643: TM-score 0.48, RMSD 4.61 Å
Elsewhere
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