UniProt P10632
P10632
P10632 (UniProt P10632): 10 experimental structures and 1 predicted model on GenesisL1. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P10632
- Experimental structures
- 10
- Predicted models
- 1
Structures
11 records of P10632 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1PQ2 | Crystal Structure of Human Drug Metabolizing Cytochrome P450 2C8 | x-ray diffraction | A, B | — | — |
| 1PQ2 | Crystal structure of human drug metabolizing cytochrome P450 2C8 | x-ray diffraction | A, B | — | — |
| 2NNH | CYP2C8dH complexed with 2 molecules of 9-cis retinoic acid | x-ray diffraction | A, B | — | — |
| 2NNH | CYP2C8DH complexed with 2 molecules of 9-cis retinoic acid | x-ray diffraction | A, B | — | — |
| 2NNI | CYP2C8dH complexed with montelukast | x-ray diffraction | A | — | — |
| 2NNI | CYP2C8DH complexed with montelukast | x-ray diffraction | A | — | — |
| 2NNJ | CYP2C8dH complexed with felodipine | x-ray diffraction | A | — | — |
| 2NNJ | CYP2C8DH complexed with felodipine | x-ray diffraction | A | — | — |
| 2VN0 | CYP2C8DH complexed with troglitazone | x-ray diffraction | A | — | — |
| 2VN0 | CYP2C8DH complexed with troglitazone | x-ray diffraction | A | — | — |
| P10632 | AlphaFold monomer V2.0 prediction for cytochrome P450 2C8 (P10632) | predicted | A | — | — |
Experiment against prediction
- 2NNJ chain A against the predicted model P10632: TM-score 0.98, RMSD 1.15 Å
- 2NNJ chain A against the predicted model P10632: TM-score 0.98, RMSD 1.15 Å
- 1PQ2 chain A against the predicted model P10632: TM-score 0.98, RMSD 1.19 Å
- 1PQ2 chain A against the predicted model P10632: TM-score 0.98, RMSD 1.19 Å
- 2NNI chain A against the predicted model P10632: TM-score 0.98, RMSD 1.21 Å
- 2NNI chain A against the predicted model P10632: TM-score 0.98, RMSD 1.21 Å
- 2NNH chain B against the predicted model P10632: TM-score 0.98, RMSD 1.22 Å
- 2NNH chain B against the predicted model P10632: TM-score 0.98, RMSD 1.22 Å
- 1PQ2 chain B against the predicted model P10632: TM-score 0.98, RMSD 1.22 Å
- 1PQ2 chain B against the predicted model P10632: TM-score 0.98, RMSD 1.22 Å
Elsewhere
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