UniProt P10619
Lysosomal protective protein (P10619)
Lysosomal protective protein (UniProt P10619): 23 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 4 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P10619
- Protein
- Lysosomal protective protein
- Experimental structures
- 23
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 4 · 1 record with a druggable one
Structures
24 records of P10619 in the MolNFT archive: 23 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1IVY | Physiological dimer hpp precursor | x-ray diffraction | A, B | — | — |
| 1IVY | Physiological dimer hpp precursor | x-ray diffraction | A, B | — | — |
| 3BP4 | The high resolution crystal structure of HLA-B*2705 in complex with a Cathepsin A signal sequence… | x-ray diffraction | C | — | — |
| 3BP4 | The high resolution crystal structure of HLA-B*2705 in complex with a cathepsin a signal sequence… | x-ray diffraction | C | — | — |
| 3BP7 | The high resolution crystal structure of HLA-B*2709 in complex with a Cathepsin A signal sequence… | x-ray diffraction | C | — | — |
| 3BP7 | The high resolution crystal structure of HLA-B*2709 in complex with a cathepsin a signal sequence… | x-ray diffraction | C | — | — |
| 3BXN | The high resolution crystal structure of HLA-B*1402 complexed with a Cathepsin A signal sequence… | x-ray diffraction | C | — | — |
| 3BXN | The high resolution crystal structure of HLA-B*1402 complexed with a cathepsin a signal sequence… | x-ray diffraction | C | — | — |
| 4AZ0 | crystal structure of cathepsin a, complexed with 8a. | x-ray diffraction | A, B | — | — |
| 4AZ0 | Crystal structure of cathepsin a, complexed with 8A. | x-ray diffraction | A, B | — | — |
| 4AZ3 | crystal structure of cathepsin a, complexed with 15a | x-ray diffraction | A, B | — | — |
| 4AZ3 | Crystal structure of cathepsin a, complexed with 15A | x-ray diffraction | A, B | — | — |
| 4CI9 | Crystal structure of cathepsin A, apo-structure | x-ray diffraction | A | — | — |
| 4CI9 | Crystal structure of cathepsin a, apo-structure | x-ray diffraction | A | — | — |
| 4CIA | Crystal structure of cathepsin A, complexed with compound 1 | x-ray diffraction | A | — | — |
| 4CIA | Crystal structure of cathepsin a, complexed with compound 1 | x-ray diffraction | A | — | — |
| 4CIB | crystal structure of cathepsin a, complexed with compound 2 | x-ray diffraction | A | — | — |
| 4CIB | Crystal structure of cathepsin a, complexed with compound 2 | x-ray diffraction | A | — | — |
| 4MWS | Crystal structure of human PPCA (trigonal crystal form 1) | x-ray diffraction | A, B | — | — |
| 4MWS | Crystal structure of human ppca (trigonal crystal form 1) | x-ray diffraction | A, B | — | — |
| 4MWT | Crystal structure of human PPCA (trigonal crystal form 2) | x-ray diffraction | A, B | — | — |
| 4MWT | Crystal structure of human ppca (trigonal crystal form 2) | x-ray diffraction | A, B | — | — |
| 6WIA | Crystal structure of human protective PROTEIN/CATHEPSIN a, dfp- inhibited (aged) | x-ray diffraction | A | NAG, CD | — |
| P10619 | AlphaFold monomer V2.0 prediction for lysosomal protective protein (P10619) | predicted | A | — | 4 (best 0.75) |
Ligands
Experiment against prediction
- 1IVY chain A against the predicted model P10619: TM-score 1.00, RMSD 0.36 Å
- 1IVY chain A against the predicted model P10619: TM-score 1.00, RMSD 0.36 Å
- 4MWT chain A against the predicted model P10619: TM-score 1.00, RMSD 0.49 Å
- 4MWT chain A against the predicted model P10619: TM-score 1.00, RMSD 0.49 Å
- 4MWS chain A against the predicted model P10619: TM-score 1.00, RMSD 0.50 Å
- 4MWS chain A against the predicted model P10619: TM-score 1.00, RMSD 0.50 Å
- 4CIA chain A against the predicted model P10619: TM-score 0.99, RMSD 0.47 Å
- 4CIA chain A against the predicted model P10619: TM-score 0.99, RMSD 0.47 Å
- 4AZ0 chain A against the predicted model P10619: TM-score 0.99, RMSD 0.56 Å
- 4AZ0 chain A against the predicted model P10619: TM-score 0.99, RMSD 0.56 Å
Elsewhere
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