UniProt P10614
Lanosterol 14-alpha demethylase (P10614)
Lanosterol 14-alpha demethylase (UniProt P10614), EC 1.14.13.70: 4 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 5 pockets. Binding sites, druggability and experiment against prediction (TM-score)…
- UniProt
- P10614
- Protein
- Lanosterol 14-alpha demethylase
- EC
- 1.14.13.70
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 5 · 1 record with a druggable one
Structures
5 records of P10614 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4LXJ | Saccharomyces cerevisiae lanosterol 14-alpha demethylase with lanosterol bound | x-ray diffraction | A | — | — |
| 4LXJ | Saccharomyces cerevisiae lanosterol 14-alpha demethylase with lanosterol bound | x-ray diffraction | A | — | — |
| 5EQB | Crystal structure of lanosterol 14-alpha demethylase with intact transmembrane domain bound to… | x-ray diffraction | A | HEM, 1YN | 5 (best 0.87) |
| 5EQB | Crystal structure of lanosterol 14-alpha demethylase with intact transmembrane domain bound to… | x-ray diffraction | A | — | — |
| P10614 | AlphaFold monomer V2.0 prediction for lanosterol 14-alpha demethylase (P10614) | predicted | A | — | — |
Ligands
Experiment against prediction
- 4LXJ chain A against the predicted model P10614: TM-score 0.99, RMSD 0.51 Å
- 4LXJ chain A against the predicted model P10614: TM-score 0.99, RMSD 0.51 Å
- 5EQB chain A against the predicted model P10614: TM-score 0.98, RMSD 0.72 Å
- 5EQB chain A against the predicted model P10614: TM-score 0.98, RMSD 0.72 Å
Elsewhere
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