UniProt P10021

Transposase for transposon Tn4430 (P10021)

Transposase for transposon Tn4430 (UniProt P10021): 4 experimental structures and 1 predicted model on GenesisL1, 91 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.

UniProt: P10021
Protein: Transposase for transposon Tn4430
Experimental structures: 4
Predicted models: 1
Pockets: 91 · 5 records with a druggable one

Structures

5 records of P10021 in the MolNFT archive: 4 experimental, 1 predicted.

Entry	Title	Method	Chains	Ligands	Pockets
7QD4	Cryo-EM structure of Tn4430 TnpA transposase from Tn3 family in complex with 100 bp long transposon…	electron microscopy	A, D	—	20 (best 0.83)
7QD5	Cryo-EM structure of Tn4430 TnpA transposase from Tn3 family in complex with 48 bp long transposon…	electron microscopy	A, D	—	20 (best 0.84)
7QD6	Cryo-EM structure of Tn4430 TnpA transposase from Tn3 family in complex with strand-transfer like…	electron microscopy	A, D	—	20 (best 0.85)
7QD8	Cryo-EM structure of Tn4430 TnpA transposase from Tn3 family in apo state	electron microscopy	A, B	—	20 (best 0.86)
P10021	AlphaFold monomer V2.0 prediction for transposase for transposon TN4430 (P10021)	predicted	A	—	11 (best 0.75)

Experiment against prediction

7QD4 chain D against the predicted model P10021: TM-score 0.86, RMSD 4.11 Å
7QD4 chain A against the predicted model P10021: TM-score 0.86, RMSD 4.11 Å
7QD6 chain A against the predicted model P10021: TM-score 0.86, RMSD 4.19 Å
7QD6 chain D against the predicted model P10021: TM-score 0.86, RMSD 4.20 Å
7QD5 chain D against the predicted model P10021: TM-score 0.85, RMSD 4.35 Å
7QD5 chain A against the predicted model P10021: TM-score 0.85, RMSD 4.38 Å
7QD8 chain B against the predicted model P10021: TM-score 0.71, RMSD 5.86 Å
7QD8 chain A against the predicted model P10021: TM-score 0.71, RMSD 5.84 Å

Elsewhere

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