UniProt P0DPB8
CRISPR-associated endoribonuclease Cas13a (P0DPB8)
CRISPR-associated endoribonuclease Cas13a (UniProt P0DPB8), EC 3.1.-.-: 4 experimental structures and 1 predicted model on GenesisL1, 20 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P0DPB8
- Protein
- CRISPR-associated endoribonuclease Cas13a
- EC
- 3.1.-.-
- Experimental structures
- 4
- Predicted models
- 1
- Pockets
- 20 · 1 record with a druggable one
Structures
5 records of P0DPB8 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6VRB | Cryo-EM structure of AcrVIA1-Cas13(crRNA) complex | electron microscopy | A | — | — |
| 6VRB | Cryo-EM structure of ACRVIA1-CAS13(CRRNA) complex | electron microscopy | A | — | — |
| 6VRC | Cryo-EM structure of Cas13(crRNA) | electron microscopy | A | — | 20 (best 0.88) |
| 6VRC | Cryo-EM structure of CAS13(CRRNA) | electron microscopy | A | — | — |
| P0DPB8 | AlphaFold monomer V2.0 prediction for CRISPR-associated endoribonuclease CAS13A (P0DPB8) | predicted | A | — | — |
Experiment against prediction
- 6VRB chain A against the predicted model P0DPB8: TM-score 0.87, RMSD 4.37 Å
- 6VRB chain A against the predicted model P0DPB8: TM-score 0.87, RMSD 4.37 Å
- 6VRC chain A against the predicted model P0DPB8: TM-score 0.86, RMSD 4.44 Å
- 6VRC chain A against the predicted model P0DPB8: TM-score 0.86, RMSD 4.44 Å
Elsewhere
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