UniProt P0DOY2
2F12 Fab Light chain (P0DOY2)
2F12 Fab Light chain (UniProt P0DOY2): 8 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 26 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P0DOY2
- Protein
- 2F12 Fab Light chain
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 26 · 4 records with a druggable one
Structures
9 records of P0DOY2 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4EOW | Crystal structure of a disease-associated anti-human GM-CSF autoantibody MB007 | x-ray diffraction | L | — | — |
| 4EOW | Crystal structure of a disease-associated anti-human gm-csf autoantibody MB007 | x-ray diffraction | L | — | — |
| 6UMX | Structural basis for specific inhibition of extracellular activation of PRO/LATENT myostatin by… | x-ray diffraction | L, l | — | — |
| 8ECQ | Bovine Fab 2G3 | x-ray diffraction | L | — | 5 (best 0.53) |
| 8ECV | Bovine Fab 2F12 | x-ray diffraction | L, A | — | 5 (best 0.56) |
| 8ECZ | Bovine Fab 4C1 | x-ray diffraction | L, A | PO4 | 8 (best 0.74) |
| 8ED1 | Bovine Fab 5C1 | x-ray diffraction | L | PO4 | 5 (best 0.52) |
| 8EDF | Bovine Fab SKD in complex with Sars COV-2 receptor binding domain | x-ray diffraction | L | — | 3 (best 0.39) |
| P0DOY2 | AlphaFold monomer V2.0 prediction for immunoglobulin lambda constant 2 (P0DOY2) | predicted | A | — | — |
Ligands
- PO4 · Phosphate ion · in 2 records
Experiment against prediction
- 6UMX chain L against the predicted model P0DOY2: TM-score 0.49, RMSD 0.59 Å
- 8ECQ chain L against the predicted model P0DOY2: TM-score 0.49, RMSD 0.62 Å
- 8ED1 chain L against the predicted model P0DOY2: TM-score 0.49, RMSD 0.67 Å
- 8ECZ chain A against the predicted model P0DOY2: TM-score 0.49, RMSD 0.72 Å
- 8ECV chain L against the predicted model P0DOY2: TM-score 0.49, RMSD 0.35 Å
- 8ECZ chain L against the predicted model P0DOY2: TM-score 0.48, RMSD 0.73 Å
- 8ECV chain A against the predicted model P0DOY2: TM-score 0.49, RMSD 0.40 Å
- 8EDF chain L against the predicted model P0DOY2: TM-score 0.48, RMSD 0.83 Å
- 6UMX chain l against the predicted model P0DOY2: TM-score 0.49, RMSD 0.51 Å
- 4EOW chain L against the predicted model P0DOY2: TM-score 0.48, RMSD 0.37 Å
Elsewhere
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