UniProt P0DOX7
Fab 2G12, light chain (P0DOX7)
Fab 2G12, light chain (UniProt P0DOX7): 27 experimental structures and 1 predicted model on GenesisL1, 6 ligands bound, 18 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P0DOX7
- Protein
- Fab 2G12, light chain
- Experimental structures
- 27
- Predicted models
- 1
- Ligands
- 6
- Pockets
- 18 · 3 records with a druggable one
Structures
28 records of P0DOX7 in the MolNFT archive: 27 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4NM4 | Crystal structure of broadly neutralizing antibody CR8043 | x-ray diffraction | L, M | — | — |
| 4NM4 | Crystal structure of broadly neutralizing antibody CR8043 | x-ray diffraction | L, M | — | — |
| 4NM8 | Crystal structure of broadly neutralizing antibody CR8043 bound to H3 influenza hemagglutinin | x-ray diffraction | L, M, N | — | — |
| 4NM8 | Crystal structure of broadly neutralizing antibody CR8043 bound to H3 influenza hemagglutinin | x-ray diffraction | L, M, N | — | — |
| 5VIC | Crystal structure of anti-zika antibody Z004 bound to denv-1 envelope protein diii | x-ray diffraction | L | — | — |
| 5VIG | Crystal structure of anti-zika antibody Z006 bound to zika virus envelope protein diii | x-ray diffraction | L, B | — | — |
| 5W1K | Junv GP1 CR1-10 Fab CR1-28 Fab complex | x-ray diffraction | A, F, K, S | NAG | — |
| 6BF7 | Cryo-EM structure of human insulin degrading enzyme in complex with FAB H11-E heavy chain, FAB… | electron microscopy | D, F | — | — |
| 6BF7 | Cryo-EM structure of human insulin degrading enzyme in complex with Fab H11-E heavy chain, Fab… | electron microscopy | D, F | — | — |
| 6BF9 | Cryo-EM structure of human insulin degrading enzyme in complex with Fab H11-E heavy chain, Fab… | electron microscopy | D, F | — | — |
| 6MSY | Anti-HIV-1 Fab Fab 2G12 + Man4 re-refinement | x-ray diffraction | L | MAN, UNX | — |
| 6MSY | Anti-HIV-1 Fab Fab 2G12 + MAN4 re-refinement | x-ray diffraction | L | MAN, UNX | — |
| 6MU3 | Anti-HIV-1 Fab 2G12 + Man7 re-refinement | x-ray diffraction | L, K | MAN | 6 (best 0.65) |
| 6MU3 | Anti-HIV-1 Fab 2G12 + MAN7 re-refinement | x-ray diffraction | L, K | MAN | — |
| 6MUB | Anti-HIV-1 Fab 2G12 + MAN5 re-refinement | x-ray diffraction | L, K | BMA, MAN | — |
| 6N2X | Anti-HIV-1 Fab 2G12 + MAN9 re-refinement | x-ray diffraction | L, K | MAN | — |
| 6N32 | Anti-HIV-1 Fab 2G12 re-refinement | x-ray diffraction | L, M | SO4 | — |
| 6N32 | Anti-HIV-1 Fab 2G12 re-refinement | x-ray diffraction | L, M | SO4 | — |
| 6N35 | Anti-HIV-1 Fab 2G12 + MAN1-2 re-refinement | x-ray diffraction | L, K | MAN, BEZ | — |
| 6NQD | Cryo-EM structure of T/F100 SOSIP.664 HIV-1 Env trimer in complex with 8ANC195 Fab | electron microscopy | D, H, L | NAG, BMA, MAN | — |
| 6NQD | Cryo-EM structure of T/F100 SOSIP.664 HIV-1 env trimer in complex with 8ANC195 Fab | electron microscopy | D, H, L | NAG, BMA, MAN | — |
| 6UOE | 3-25 Fab germline-reversion variant bound to an HCMV gB-derived peptide | x-ray diffraction | L | — | 4 (best 0.53) |
| 6UOE | 3-25 Fab germline-reversion variant bound to an hcmv gb-derived peptide | x-ray diffraction | L | — | — |
| 6UTA | Crystal structure of Z004 iGL Fab in complex with ZIKV EDIII | x-ray diffraction | L, B | — | 8 (best 0.64) |
| 6UTA | Crystal structure of Z004 igl Fab in complex with zikv ediii | x-ray diffraction | L, B | — | — |
| 6UTE | Crystal structure of Z032 Fab in complex with WNV EDIII | x-ray diffraction | D, B, F, H, J | — | — |
| 6UTE | Crystal structure of Z032 Fab in complex with wnv ediii | x-ray diffraction | D, B, F, H, J | — | — |
| P0DOX7 | AlphaFold monomer V2.0 prediction for immunoglobulin kappa light chain (P0DOX7) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6UTE chain D against the predicted model P0DOX7: TM-score 0.98, RMSD 0.68 Å
- 6UTE chain D against the predicted model P0DOX7: TM-score 0.98, RMSD 0.68 Å
- 6UTE chain H against the predicted model P0DOX7: TM-score 0.98, RMSD 0.75 Å
- 6UTE chain H against the predicted model P0DOX7: TM-score 0.98, RMSD 0.75 Å
- 5W1K chain A against the predicted model P0DOX7: TM-score 0.97, RMSD 0.88 Å
- 5VIC chain L against the predicted model P0DOX7: TM-score 0.97, RMSD 0.98 Å
- 4NM4 chain L against the predicted model P0DOX7: TM-score 0.95, RMSD 0.95 Å
- 4NM4 chain L against the predicted model P0DOX7: TM-score 0.95, RMSD 0.95 Å
- 6UTA chain L against the predicted model P0DOX7: TM-score 0.97, RMSD 1.07 Å
- 6UTA chain L against the predicted model P0DOX7: TM-score 0.97, RMSD 1.07 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.