UniProt P0CZ01
Hyaluronate lyase (P0CZ01)
Hyaluronate lyase (UniProt P0CZ01), EC 4.2.2.1: 2 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 19 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P0CZ01
- Protein
- Hyaluronate lyase
- EC
- 4.2.2.1
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 19 · 2 records with a druggable one
Structures
3 records of P0CZ01 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8FNX | Crystal structure of Hyaluronate lyase B from Cutibacterium acnes | x-ray diffraction | A | PO4 | 6 (best 0.65) |
| 8G0O | Crystal structure of Y281F mutant of Hyaluronate lyase B from Cutibacterium acnes | x-ray diffraction | A, B | — | 13 (best 0.66) |
| P0CZ01 | AlphaFold monomer V2.0 prediction for hyaluronate lyase (P0CZ01) | predicted | A | — | — |
Ligands
- PO4 · Phosphate ion · in 1 record
Experiment against prediction
- 8FNX chain A against the predicted model P0CZ01: TM-score 0.93, RMSD 2.66 Å
- 8G0O chain A against the predicted model P0CZ01: TM-score 0.91, RMSD 3.00 Å
- 8G0O chain B against the predicted model P0CZ01: TM-score 0.91, RMSD 3.01 Å
Elsewhere
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