UniProt P0CI39
Pheromone alpha factor receptor (P0CI39)
Pheromone alpha factor receptor (UniProt P0CI39): 10 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 39 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P0CI39
- Protein
- Pheromone alpha factor receptor
- Experimental structures
- 10
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 39 · 6 records with a druggable one
Structures
11 records of P0CI39 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7AD3 | Class D GPCR Ste2 dimer coupled to two G proteins | electron microscopy | B, A | NAG, Y01 | 10 (best 0.70) |
| 7AD3 | Class D GPCR STE2 dimer coupled to two G proteins | electron microscopy | B, A | NAG, Y01 | — |
| 7QA8 | Structure of the GPCR dimer Ste2 bound to an antagonist | electron microscopy | A, B | NAG, Y01 | 6 (best 0.69) |
| 7QA8 | Structure of the GPCR dimer STE2 bound to an antagonist | electron microscopy | A, B | NAG, Y01 | — |
| 7QB9 | Structure of the ligand-free GPCR dimer Ste2 | electron microscopy | A, B | NAG, Y01 | 7 (best 0.73) |
| 7QB9 | Structure of the ligand-free GPCR dimer STE2 | electron microscopy | A, B | NAG, Y01 | — |
| 7QBC | Structure of the GPCR dimer Ste2 in the inactive-like state bound to agonist | electron microscopy | A, B | NAG, Y01 | 6 (best 0.65) |
| 7QBC | Structure of the GPCR dimer STE2 in the inactive-like state bound to agonist | electron microscopy | A, B | NAG, Y01 | — |
| 7QBI | Structure of the GPCR dimer Ste2 in the active-like state bound to agonist | electron microscopy | A, B | NAG, Y01 | 7 (best 0.59) |
| 7QBI | Structure of the GPCR dimer STE2 in the active-like state bound to agonist | electron microscopy | A, B | NAG, Y01 | — |
| P0CI39 | AlphaFold monomer V2.0 prediction for pheromone alpha factor receptor (P0CI39) | predicted | A | — | 3 (best 0.75) |
Ligands
Experiment against prediction
- 7AD3 chain A against the predicted model P0CI39: TM-score 0.92, RMSD 2.15 Å
- 7AD3 chain B against the predicted model P0CI39: TM-score 0.92, RMSD 2.05 Å
- 7AD3 chain B against the predicted model P0CI39: TM-score 0.92, RMSD 2.05 Å
- 7QBI chain A against the predicted model P0CI39: TM-score 0.92, RMSD 2.11 Å
- 7QBI chain A against the predicted model P0CI39: TM-score 0.92, RMSD 2.11 Å
- 7QA8 chain A against the predicted model P0CI39: TM-score 0.89, RMSD 2.69 Å
- 7QA8 chain A against the predicted model P0CI39: TM-score 0.89, RMSD 2.69 Å
- 7QBC chain A against the predicted model P0CI39: TM-score 0.88, RMSD 2.74 Å
- 7QBC chain A against the predicted model P0CI39: TM-score 0.88, RMSD 2.74 Å
- 7QB9 chain A against the predicted model P0CI39: TM-score 0.88, RMSD 2.81 Å
Elsewhere
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