UniProt P0CG72
Polyubiquitin (P0CG72)
Polyubiquitin (UniProt P0CG72): 3 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 17 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P0CG72
- Protein
- Polyubiquitin
- Experimental structures
- 3
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 17 · 3 records with a druggable one
Structures
4 records of P0CG72 in the MolNFT archive: 3 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 9B5F | Ubiquitin E1-Ub-E2 tetrahedral transthiolation intermediate mimic (doubly Ub-loaded) - cluster 1… | electron microscopy | B | ATP | 5 (best 0.79) |
| 9B5I | Ubiquitin E1-Ub-E2 tetrahedral transthiolation intermediate mimic (doubly Ub-loaded) - cluster 4… | electron microscopy | B | AMP | 6 (best 0.79) |
| 9B5L | Ubiquitin E1-Ub-E2 tetrahedral transthiolation intermediate mimic (doubly Ub-loaded) - Ub(T) class… | electron microscopy | B | AMP | 6 (best 0.78) |
| P0CG72 | AlphaFold monomer V2.0 prediction for polyubiquitin (P0CG72) | predicted | A | — | — |
Ligands
Experiment against prediction
- 9B5F chain B against the predicted model P0CG72: TM-score 0.91, RMSD 1.41 Å
- 9B5I chain B against the predicted model P0CG72: TM-score 0.91, RMSD 1.09 Å
- 9B5L chain B against the predicted model P0CG72: TM-score 0.90, RMSD 1.09 Å
Elsewhere
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