UniProt P0C0S8
Histone H2A type 1 (P0C0S8)
Histone H2A type 1 (UniProt P0C0S8): 33 experimental structures on GenesisL1, 227 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P0C0S8
- Protein
- Histone H2A type 1
- Experimental structures
- 33
- Predicted models
- 0
- Pockets
- 227 · 19 records with a druggable one
Structures
33 records of P0C0S8 in the MolNFT archive: 33 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4QYL | Crystal Structure of the human BRPF1 bromodomain in complex with a histone H2AK5ac peptide | x-ray diffraction | E, F, G, H | — | — |
| 4QYL | Crystal structure of the human BRPF1 bromodomain in complex with a histone H2AK5AC peptide | x-ray diffraction | E, F, G, H | — | — |
| 5KGF | Structural model of 53BP1 bound to a ubiquitylated and methylated nucleosome, at 4.5 A resolution | electron microscopy | C, G | — | 14 (best 0.78) |
| 5KGF | Structural model of 53BP1 bound to a ubiquitylated and methylated nucleosome, at 4.5 a resolution | electron microscopy | C, G | — | — |
| 6R0C | Human-D02 Nucleosome Core Particle with biotin-streptavidin label | electron microscopy | C, G | — | 14 (best 0.78) |
| 6R0C | Human-D02 nucleosome core particle with biotin-streptavidin label | electron microscopy | C, G | — | — |
| 6RNY | PFV intasome - nucleosome strand transfer complex | electron microscopy | C, G | — | 13 (best 0.80) |
| 6RNY | Pfv intasome - nucleosome strand transfer complex | electron microscopy | C, G | — | — |
| 6X59 | The mouse cGAS catalytic domain binding to human assembled nucleosome | electron microscopy | C, G | — | 12 (best 0.77) |
| 6X59 | The mouse cgas catalytic domain binding to human assembled nucleosome | electron microscopy | C, G | — | — |
| 6X5A | The mouse cgas catalytic domain binding to human nucleosome that purified from HEK293T cells | electron microscopy | C, G | — | — |
| 6XJD | Two mouse cGAS catalytic domain binding to human assembled nucleosome | electron microscopy | C, G | — | — |
| 6XJD | Two mouse cgas catalytic domain binding to human assembled nucleosome | electron microscopy | C, G | — | — |
| 7E8D | NSD2 E1099K mutant bound to nucleosome | electron microscopy | C, G | — | — |
| 7JO9 | 1:1 cGAS-nucleosome complex | electron microscopy | C, G | — | 13 (best 0.76) |
| 7JO9 | 1:1 cgas-nucleosome complex | electron microscopy | C, G | — | — |
| 7JOA | 2:1 cGAS-nucleosome complex | electron microscopy | C, G | — | 12 (best 0.75) |
| 7JOA | 2:1 cgas-nucleosome complex | electron microscopy | C, G | — | — |
| 7TAN | Structure of VRK1 C-terminal tail bound to nucleosome core particle | electron microscopy | C, G | — | 12 (best 0.75) |
| 7TAN | Structure of VRK1 C-terminal tail bound to nucleosome core particle | electron microscopy | C, G | — | — |
| 7U51 | Nucleosome core particle with AP-site at SHL-6 | electron microscopy | C, G | — | 13 (best 0.79) |
| 7U52 | nucleosome core particle with AP-site at SHL-6.5 | electron microscopy | C, G | — | 13 (best 0.82) |
| 7U53 | Nucleosome core particle with AP-site at SHL0 | electron microscopy | C, G | — | 12 (best 0.80) |
| 7UV9 | KDM2A-nucleosome structure stabilized by H3K36C-UNC8015 covalent conjugate | electron microscopy | C, G | — | 9 (best 0.76) |
| 8GUJ | Bre1-nucleosome complex (Model II) | electron microscopy | C, G | — | 12 (best 0.78) |
| 8GUK | Human nucleosome core particle (free form) | electron microscopy | C, G | — | 11 (best 0.82) |
| 8OFF | Structure of BARD1 ARD-BRCTs in complex with H2AKc15ub nucleosomes (Map1) | electron microscopy | Aa, Ab | — | 11 (best 0.76) |
| 8QZM | Structure of DNMT3A1 UDR region bound to H2AK119ub nucleosome | electron microscopy | C, G | — | 11 (best 0.81) |
| 8VWS | Nucleosome containing 8oxoG at SHL-6 | electron microscopy | C, G | — | 11 (best 0.77) |
| 8VWT | OGG1 bound to a nucleosome containing 8oxoG at SHL-6 (composite map) | electron microscopy | G, C | — | 12 (best 0.80) |
| 8VWU | Nucleosome containing 8oxoG at SHL4 | electron microscopy | C, G | — | 11 (best 0.78) |
| 8VWV | OGG1 bound to a nucleosome containing 8oxoG at SHL4 (composite map) | electron microscopy | C, G | — | 11 (best 0.79) |
| P0C0S8 | AlphaFold monomer V2.0 prediction for histone H2A type 1 (P0C0S8) | — | — | — |
Elsewhere
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