UniProt P0AG30
Transcription termination factor rho (P0AG30)
Transcription termination factor rho (UniProt P0AG30), EC 3.6.4.-: 27 experimental structures and 1 predicted model on GenesisL1, 6 ligands bound, 329 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- P0AG30
- Protein
- Transcription termination factor rho
- EC
- 3.6.4.-
- Experimental structures
- 27
- Predicted models
- 1
- Ligands
- 6
- Pockets
- 329 · 18 records with a druggable one
Structures
28 records of P0AG30 in the MolNFT archive: 27 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1PV4 | X-ray crystal structure of the Rho transcription termination factor in complex with single stranded… | x-ray diffraction | A, B, C, D, E, F | — | 20 (best 0.83) |
| 1PV4 | X-ray crystal structure of the rho transcription termination factor in complex with single stranded… | x-ray diffraction | A, B, C, D, E, F | — | — |
| 1PVO | X-ray crystal structure of Rho transcription termination factor in complex with ssRNA substrate and… | x-ray diffraction | A, B, C, D, E, F | ANP | 20 (best 0.83) |
| 1PVO | X-ray crystal structure of rho transcription termination factor in complex with ssrna substrate and… | x-ray diffraction | A, B, C, D, E, F | — | — |
| 2HT1 | The closed ring structure of the Rho transcription termination factor in complex with nucleic acid… | x-ray diffraction | A, B | — | — |
| 2HT1 | The closed ring structure of the rho transcription termination factor in complex with nucleic acid… | x-ray diffraction | A, B | — | — |
| 3ICE | Rho transcription termination factor bound to RNA and ADP-BeF3 | x-ray diffraction | A, B, C, D, E, F | — | — |
| 3ICE | Rho transcription termination factor bound to RNA and ADP-BEF3 | x-ray diffraction | A, B, C, D, E, F | — | — |
| 6WA8 | Crystal structure of the E. coli transcription termination factor Rho | x-ray diffraction | A, B, C, D, E, F | ATP | 20 (best 0.83) |
| 6WA8 | Crystal structure of the E. COLI transcription termination factor rho | x-ray diffraction | A, B, C, D, E, F | ATP | — |
| 6XAS | CryoEM Structure of E. coli Rho-dependent Transcription Pre-termination Complex | electron microscopy | C, A, B, D, E, F | — | 12 (best 0.86) |
| 6XAS | Cryoem structure of E. COLI rho-dependent transcription pre- termination complex | electron microscopy | C, A, B, D, E, F | — | — |
| 6XAV | CryoEM Structure of E. coli Rho-dependent Transcription Pre-termination Complex bound with NusG | electron microscopy | C, A, B, D, E, F | — | 10 (best 0.86) |
| 6XAV | Cryoem structure of E. COLI rho-dependent transcription pre- termination complex bound with nusg | electron microscopy | C, A, B, D, E, F | — | — |
| 8PEX | Rho P167L-ATPgS-Psu complex I | electron microscopy | A, B, C, D, E, F, I, J, K, L, M, N | AGS, MG | 17 (best 0.86) |
| 8PEY | Rho P167L-ATPgS-Psu complex II | electron microscopy | A, B, C, D, E, F, G, I, J, K, L, M, N | AGS, MG | 18 (best 0.87) |
| 8PTG | Structure of the transcription termination factor Rho bound to RNA at the PBS and SBS | electron microscopy | A, B, C, D, E, F | ADP, MG, BEF | 20 (best 0.83) |
| 8PTM | Structure of the transcription termination factor Rho in complex with Rof and ADP | electron microscopy | A, B, C, D, E, F | ADP, MG | 20 (best 0.82) |
| 8PTN | Structure of the transcription termination factor Rho in complex with Rof | electron microscopy | A, B, C, D, E, F | — | 20 (best 0.90) |
| 8PTO | Structure of Rho pentamer in complex with Rof and ADP | electron microscopy | A, B, C, D, E | ADP | 20 (best 0.80) |
| 8PTP | Structure of Rho pentamer in complex with Rof | electron microscopy | A, B, C, D, E | — | 19 (best 0.82) |
| 8Q3P | Bacterial transcription termination factor Rho G150D mutant bound to ADP; C-terminal 8xHis-tag | electron microscopy | a, r, q, p, o, n, m, l, k, j, b, c, d, e, f, g, h, i | ADP, MG | 20 (best 0.84) |
| 8Q3Q | Bacterial transcription termination factor Rho G152D mutant bound to ADP; C-terminal 8xHis-tag | electron microscopy | a, r, q, p, o, n, m, l, k, j, i, h, g, f, e, d, c, b | ADP, MG | 20 (best 0.84) |
| 8W8D | Structural mechanism of inhibition of the Rho transcription termination factor by Rof | electron microscopy | A, B, C, D, E, F | — | 17 (best 0.83) |
| 9GCS | Rho-ATP-Psu complex II | electron microscopy | C, D, E, J, K, L, M, O, B, G, N, F | ATP, MG | 16 (best 0.87) |
| 9GCT | Rho-ATP-Psu complex II expanded | electron microscopy | A, B, C, D, E, F, G, H, J, K, L, M, N, O, P, Y | ATP, MG | 16 (best 0.87) |
| 9GCU | Rho-P167L-ATP gamma S | electron microscopy | A, B, C, D, E, F | MG, ADP | 20 (best 0.83) |
| P0AG30 | AlphaFold monomer V2.0 prediction for transcription termination factor rho (P0AG30) | predicted | A | — | 4 (best 0.39) |
Ligands
Experiment against prediction
- 1PV4 chain B against the predicted model P0AG30: TM-score 0.98, RMSD 0.94 Å
- 1PV4 chain B against the predicted model P0AG30: TM-score 0.98, RMSD 0.94 Å
- 8PTO chain A against the predicted model P0AG30: TM-score 0.98, RMSD 1.05 Å
- 1PVO chain B against the predicted model P0AG30: TM-score 0.98, RMSD 0.95 Å
- 1PVO chain B against the predicted model P0AG30: TM-score 0.98, RMSD 0.95 Å
- 8PTM chain A against the predicted model P0AG30: TM-score 0.98, RMSD 1.10 Å
- 8PTP chain A against the predicted model P0AG30: TM-score 0.98, RMSD 1.14 Å
- 1PVO chain A against the predicted model P0AG30: TM-score 0.98, RMSD 1.08 Å
- 1PVO chain A against the predicted model P0AG30: TM-score 0.98, RMSD 1.08 Å
- 3ICE chain B against the predicted model P0AG30: TM-score 0.98, RMSD 1.16 Å
Elsewhere
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