UniProt P0AG16
Amidophosphoribosyltransferase (P0AG16)
Amidophosphoribosyltransferase (UniProt P0AG16), EC 2.4.2.14: 5 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 54 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- P0AG16
- Protein
- Amidophosphoribosyltransferase
- EC
- 2.4.2.14
- Experimental structures
- 5
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 54 · 4 records with a druggable one
Structures
6 records of P0AG16 in the MolNFT archive: 5 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6CZF | The structure of E. coli PurF in complex with ppGpp-Mg | x-ray diffraction | A, B, C, D | MG, G4P | 20 (best 0.85) |
| 6CZF | The structure of E. COLI purf in complex with ppgpp-mg | x-ray diffraction | A, B, C, D | G4P, MG | — |
| 6OTT | Structure of PurF in complex with ppApp | x-ray diffraction | A, B | N7Y | 11 (best 0.85) |
| 6OTT | Structure of purf in complex with ppapp | x-ray diffraction | A, B | N7Y | — |
| 8W7D | Crystal structure of EcPPAT-FR901483 complex | x-ray diffraction | A, B, C, D | 7TG | 20 (best 0.86) |
| P0AG16 | AlphaFold monomer V2.0 prediction for amidophosphoribosyltransferase (P0AG16) | predicted | A | — | 3 (best 0.80) |
Ligands
- G4P · Guanosine-5',3'-tetraphosphate · in 2 records
- MG · Magnesium ion · in 2 records
- N7Y · adenosine 3',5'-bis(trihydrogen diphosphate) · in 2 records
- 7TG · [(1S,3S,6S,7S,8R,9S)-6-[(4-methoxyphenyl)methyl]-3-(methylamino)-7-oxidanyl-5-azatricyclo[6.3.1.0^1,5]dodecan-9-yl] dihydrogen phosphate · in 1 record
Experiment against prediction
- 8W7D chain B against the predicted model P0AG16: TM-score 0.99, RMSD 0.89 Å
- 8W7D chain D against the predicted model P0AG16: TM-score 0.99, RMSD 1.05 Å
- 8W7D chain C against the predicted model P0AG16: TM-score 0.97, RMSD 1.42 Å
- 8W7D chain A against the predicted model P0AG16: TM-score 0.97, RMSD 1.46 Å
- 6CZF chain D against the predicted model P0AG16: TM-score 0.97, RMSD 1.69 Å
- 6CZF chain D against the predicted model P0AG16: TM-score 0.97, RMSD 1.69 Å
- 6CZF chain B against the predicted model P0AG16: TM-score 0.97, RMSD 1.71 Å
- 6CZF chain B against the predicted model P0AG16: TM-score 0.97, RMSD 1.71 Å
- 6OTT chain A against the predicted model P0AG16: TM-score 0.96, RMSD 1.79 Å
- 6OTT chain A against the predicted model P0AG16: TM-score 0.96, RMSD 1.79 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.