UniProt P0AFX0
Ribosome hibernation promoting factor (P0AFX0)
Ribosome hibernation promoting factor (UniProt P0AFX0): 4 experimental structures and 1 predicted model on GenesisL1, 2 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P0AFX0
- Protein
- Ribosome hibernation promoting factor
- Experimental structures
- 4
- Predicted models
- 1
- Pockets
- 2 · 1 record with a druggable one
Structures
5 records of P0AFX0 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4V8H | Crystal structure of HPF bound to the 70S ribosome. | x-ray diffraction | AX, CX | — | — |
| 6H4N | Structure of a hibernating 100S ribosome reveals an inactive conformation of the ribosomal protein… | electron microscopy | x | — | — |
| 6H58 | Structure of a hibernating 100S ribosome reveals an inactive conformation of the ribosomal protein… | electron microscopy | x, xx | — | — |
| 6Y69 | Cryo-EM structure of an Escherichia coli 70S ribosome in complex with antibiotic TetracenomycinX | electron microscopy | x | — | 2 (best 0.87) |
| P0AFX0 | AlphaFold monomer V2.0 prediction for ribosome hibernation promoting factor (P0AFX0) | predicted | A | — | — |
Experiment against prediction
- 6H4N chain x against the predicted model P0AFX0: TM-score 0.96, RMSD 0.91 Å
- 6H58 chain x against the predicted model P0AFX0: TM-score 0.96, RMSD 0.91 Å
- 6Y69 chain x against the predicted model P0AFX0: TM-score 0.96, RMSD 1.06 Å
- 4V8H chain AX against the predicted model P0AFX0: TM-score 0.94, RMSD 1.04 Å
Elsewhere
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