UniProt P0AFW8
Protein rof (P0AFW8)
Protein rof (UniProt P0AFW8): 5 experimental structures and 1 predicted model on GenesisL1, 17 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P0AFW8
- Protein
- Protein rof
- Experimental structures
- 5
- Predicted models
- 1
- Pockets
- 17 · 3 records with a druggable one
Structures
6 records of P0AFW8 in the MolNFT archive: 5 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1SG5 | Solution structure of Yaeo, a Rho-specific inhibitor of transcription termination | solution nmr | A | — | — |
| 1SG5 | Solution structure of yaeo, a rho-specific inhibitor of transcription termination | solution nmr | A | — | — |
| 8PTO | Structure of Rho pentamer in complex with Rof and ADP | electron microscopy | b, c, d, a | — | 4 (best 0.61) |
| 8PTP | Structure of Rho pentamer in complex with Rof | electron microscopy | a, b, c, d | — | 4 (best 0.76) |
| 8W8D | Structural mechanism of inhibition of the Rho transcription termination factor by Rof | electron microscopy | c, e, b, a, f, d | — | 8 (best 0.65) |
| P0AFW8 | AlphaFold monomer V2.0 prediction for protein rof (P0AFW8) | predicted | A | — | 1 (best 0.41) |
Experiment against prediction
- 8PTO chain d against the predicted model P0AFW8: TM-score 0.65, RMSD 2.87 Å
- 8PTO chain c against the predicted model P0AFW8: TM-score 0.64, RMSD 2.92 Å
- 8PTO chain b against the predicted model P0AFW8: TM-score 0.64, RMSD 3.02 Å
- 8W8D chain d against the predicted model P0AFW8: TM-score 0.64, RMSD 2.79 Å
- 8PTP chain c against the predicted model P0AFW8: TM-score 0.64, RMSD 2.91 Å
- 8PTP chain d against the predicted model P0AFW8: TM-score 0.63, RMSD 3.10 Å
- 8PTO chain a against the predicted model P0AFW8: TM-score 0.63, RMSD 2.98 Å
- 8PTP chain b against the predicted model P0AFW8: TM-score 0.62, RMSD 3.01 Å
- 8W8D chain e against the predicted model P0AFW8: TM-score 0.61, RMSD 3.00 Å
- 8W8D chain c against the predicted model P0AFW8: TM-score 0.61, RMSD 3.03 Å
Elsewhere
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