UniProt P0AFG3
2-oxoglutarate dehydrogenase E1 component (P0AFG3)
2-oxoglutarate dehydrogenase E1 component (UniProt P0AFG3): 2 experimental structures and 1 predicted model on GenesisL1, 8 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P0AFG3
- Protein
- 2-oxoglutarate dehydrogenase E1 component
- Experimental structures
- 2
- Predicted models
- 1
- Pockets
- 8 · 1 record with a druggable one
Structures
3 records of P0AFG3 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2JGD | E. COLI 2-oxoglutarate dehydrogenase (E1o) | x-ray diffraction | A, B | — | — |
| 2JGD | E. COLI 2-oxoglutarate dehydrogenase (E1O) | x-ray diffraction | A, B | — | — |
| P0AFG3 | AlphaFold monomer V2.0 prediction for 2-oxoglutarate dehydrogenase E1 component (P0AFG3) | predicted | A | — | 8 (best 0.71) |
Experiment against prediction
- 2JGD chain B against the predicted model P0AFG3: TM-score 0.99, RMSD 0.73 Å
- 2JGD chain B against the predicted model P0AFG3: TM-score 0.99, RMSD 0.73 Å
- 2JGD chain A against the predicted model P0AFG3: TM-score 0.99, RMSD 0.81 Å
- 2JGD chain A against the predicted model P0AFG3: TM-score 0.99, RMSD 0.81 Å
Elsewhere
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