UniProt P0AFC3
NADH-quinone oxidoreductase subunit A (P0AFC3)
NADH-quinone oxidoreductase subunit A (UniProt P0AFC3), EC 7.1.1.-: 8 experimental structures and 1 predicted model on GenesisL1, 16 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P0AFC3
- Protein
- NADH-quinone oxidoreductase subunit A
- EC
- 7.1.1.-
- Experimental structures
- 8
- Predicted models
- 1
- Pockets
- 16 · 4 records with a druggable one
Structures
9 records of P0AFC3 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7NYH | Respiratory complex I from Escherichia coli - focused refinement of membrane arm | electron microscopy | A | — | 3 (best 0.66) |
| 7NYH | Respiratory complex I from escherichia COLI - focused refinement of membrane arm | electron microscopy | A | — | — |
| 7NYR | Respiratory complex I from Escherichia coli - conformation 1 | electron microscopy | A | — | 5 (best 0.80) |
| 7NYR | Respiratory complex I from escherichia COLI - conformation 1 | electron microscopy | A | — | — |
| 7NYU | Respiratory complex I from Escherichia coli - conformation 2 | electron microscopy | A | — | 4 (best 0.76) |
| 7NYU | Respiratory complex I from escherichia COLI - conformation 2 | electron microscopy | A | — | — |
| 7NYV | Respiratory complex I from Escherichia coli - conformation 3 | electron microscopy | A | — | 4 (best 0.76) |
| 7NYV | Respiratory complex I from escherichia COLI - conformation 3 | electron microscopy | A | — | — |
| P0AFC3 | AlphaFold monomer V2.0 prediction for NADH-quinone oxidoreductase subunit a (P0AFC3) | predicted | A | — | — |
Experiment against prediction
- 7NYH chain A against the predicted model P0AFC3: TM-score 0.78, RMSD 2.01 Å
- 7NYH chain A against the predicted model P0AFC3: TM-score 0.78, RMSD 2.01 Å
- 7NYV chain A against the predicted model P0AFC3: TM-score 0.76, RMSD 2.28 Å
- 7NYV chain A against the predicted model P0AFC3: TM-score 0.76, RMSD 2.28 Å
- 7NYU chain A against the predicted model P0AFC3: TM-score 0.75, RMSD 2.32 Å
- 7NYU chain A against the predicted model P0AFC3: TM-score 0.75, RMSD 2.32 Å
- 7NYR chain A against the predicted model P0AFC3: TM-score 0.75, RMSD 2.30 Å
- 7NYR chain A against the predicted model P0AFC3: TM-score 0.75, RMSD 2.30 Å
Elsewhere
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