UniProt P0AET8
7alpha-hydroxysteroid dehydrogenase (P0AET8)
7alpha-hydroxysteroid dehydrogenase (UniProt P0AET8), EC 1.1.1.159: 2 experimental structures and 1 predicted model on GenesisL1, 42 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P0AET8
- Protein
- 7alpha-hydroxysteroid dehydrogenase
- EC
- 1.1.1.159
- Experimental structures
- 2
- Predicted models
- 1
- Pockets
- 42 · 3 records with a druggable one
Structures
3 records of P0AET8 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7ENY | Crystal structure of hydroxysteroid dehydrogenase from Escherichia coli | x-ray diffraction | A, B, C, D, E, F, G, H | — | 20 (best 0.79) |
| 7ENY | Crystal structure of hydroxysteroid dehydrogenase from escherichia COLI | x-ray diffraction | A, B, C, D, E, F, G, H | — | 20 (best 0.79) |
| P0AET8 | AlphaFold monomer V2.0 prediction for 7ALPHA-hydroxysteroid dehydrogenase (P0AET8) | predicted | A | — | 2 (best 0.69) |
Experiment against prediction
- 7ENY chain D against the predicted model P0AET8: TM-score 0.98, RMSD 0.80 Å
- 7ENY chain D against the predicted model P0AET8: TM-score 0.98, RMSD 0.80 Å
- 7ENY chain E against the predicted model P0AET8: TM-score 0.98, RMSD 0.83 Å
- 7ENY chain A against the predicted model P0AET8: TM-score 0.98, RMSD 0.85 Å
- 7ENY chain A against the predicted model P0AET8: TM-score 0.98, RMSD 0.85 Å
- 7ENY chain H against the predicted model P0AET8: TM-score 0.98, RMSD 0.99 Å
- 7ENY chain H against the predicted model P0AET8: TM-score 0.98, RMSD 0.99 Å
- 7ENY chain G against the predicted model P0AET8: TM-score 0.97, RMSD 1.27 Å
- 7ENY chain G against the predicted model P0AET8: TM-score 0.97, RMSD 1.27 Å
- 7ENY chain F against the predicted model P0AET8: TM-score 0.96, RMSD 1.40 Å
Elsewhere
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