UniProt P0AEJ3
Isochorismate synthase EntC (P0AEJ3)
Isochorismate synthase EntC (UniProt P0AEJ3), EC 5.4.4.2: 6 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 45 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P0AEJ3
- Protein
- Isochorismate synthase EntC
- EC
- 5.4.4.2
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 45 · 3 records with a druggable one
Structures
7 records of P0AEJ3 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5JXZ | A low magnesium structure of the isochorismate synthase, EntC | x-ray diffraction | A, B | MG, ISC, ISJ | 16 (best 0.80) |
| 5JXZ | A low magnesium structure of the isochorismate synthase, entc | x-ray diffraction | A, B | — | — |
| 5JY4 | A high magnesium structure of the isochorismate synthase, EntC | x-ray diffraction | A, B | MG, ISC | 16 (best 0.79) |
| 5JY4 | A high magnesium structure of the isochorismate synthase, entc | x-ray diffraction | A, B | — | — |
| 5JY8 | An iron-bound structure of the isochorismate synthase EntC | x-ray diffraction | A, B | FE, ISJ | 13 (best 0.80) |
| 5JY8 | An iron-bound structure of the isochorismate synthase entc | x-ray diffraction | A, B | — | — |
| P0AEJ3 | AlphaFold monomer V2.0 prediction for isochorismate synthase entc (P0AEJ3) | predicted | A | — | — |
Ligands
Experiment against prediction
- 5JXZ chain B against the predicted model P0AEJ3: TM-score 0.99, RMSD 0.49 Å
- 5JXZ chain B against the predicted model P0AEJ3: TM-score 0.99, RMSD 0.49 Å
- 5JY8 chain B against the predicted model P0AEJ3: TM-score 0.99, RMSD 0.54 Å
- 5JY8 chain B against the predicted model P0AEJ3: TM-score 0.99, RMSD 0.54 Å
- 5JY4 chain B against the predicted model P0AEJ3: TM-score 0.99, RMSD 0.55 Å
- 5JY4 chain B against the predicted model P0AEJ3: TM-score 0.99, RMSD 0.55 Å
- 5JY8 chain A against the predicted model P0AEJ3: TM-score 0.99, RMSD 0.61 Å
- 5JY8 chain A against the predicted model P0AEJ3: TM-score 0.99, RMSD 0.61 Å
- 5JXZ chain A against the predicted model P0AEJ3: TM-score 0.99, RMSD 0.64 Å
- 5JXZ chain A against the predicted model P0AEJ3: TM-score 0.99, RMSD 0.64 Å
Elsewhere
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