UniProt P0AE82
Sensor histidine kinase CpxA (P0AE82)
Sensor histidine kinase CpxA (UniProt P0AE82), EC 2.7.13.3: 17 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 1 pocket. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- P0AE82
- Protein
- Sensor histidine kinase CpxA
- EC
- 2.7.13.3
- Experimental structures
- 17
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 1 · 0 records with a druggable one
Structures
18 records of P0AE82 in the MolNFT archive: 17 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4BIU | Crystal structure of CpxAHDC (orthorhombic form 1) | x-ray diffraction | A, B, C, D, E, F | — | — |
| 4BIU | Crystal structure of cpxahdc (orthorhombic form 1) | x-ray diffraction | A, B, C, D, E, F | — | — |
| 4BIV | Crystal structure of CpxAHDC (trigonal form) | x-ray diffraction | A, B | — | — |
| 4BIV | Crystal structure of cpxahdc (trigonal form) | x-ray diffraction | A, B | — | — |
| 4BIW | Crystal structure of CpxAHDC (hexagonal form) | x-ray diffraction | A, B | — | — |
| 4BIW | Crystal structure of cpxahdc (hexagonal form) | x-ray diffraction | A, B | — | — |
| 4BIX | Crystal structure of CpxAHDC (monoclinic form 1) | x-ray diffraction | A, B | — | — |
| 4BIX | Crystal structure of cpxahdc (monoclinic form 1) | x-ray diffraction | A, B | — | — |
| 4BIY | Crystal structure of CpxAHDC (monoclinic form 2) | x-ray diffraction | A, B, C, D | — | — |
| 4BIY | Crystal structure of cpxahdc (monoclinic form 2) | x-ray diffraction | A, B, C, D | — | — |
| 4BIZ | Crystal structure of CpxAHDC (orthorhombic form 2) | x-ray diffraction | A, B, C, D, E, F | — | — |
| 4BIZ | Crystal structure of cpxahdc (orthorhombic form 2) | x-ray diffraction | A, B, C, D, E, F | — | — |
| 4CB0 | Crystal structure of CpxAHDC in complex with ATP (hexagonal form) | x-ray diffraction | A, B | — | — |
| 4CB0 | Crystal structure of cpxahdc in complex with ATP (hexagonal form) | x-ray diffraction | A, B | — | — |
| 5LFK | Crystal structure of CpxAHDC (hemiphosphorylated form) | x-ray diffraction | A, B | SO4, ATP, MG | — |
| 5LFK | Crystal structure of cpxahdc (hemiphosphorylated form) | x-ray diffraction | A, B | SO4, ATP, MG | — |
| 8UK7 | Periplasmic domain of Escherichia coli CpxA | x-ray diffraction | A, B | — | 1 (best 0.46) |
| P0AE82 | AlphaFold monomer V2.0 prediction for sensor histidine kinase cpxa (P0AE82) | predicted | A | — | — |
Ligands
Experiment against prediction
- 8UK7 chain B against the predicted model P0AE82: TM-score 0.97, RMSD 0.87 Å
- 8UK7 chain A against the predicted model P0AE82: TM-score 0.96, RMSD 0.97 Å
- 4BIU chain F against the predicted model P0AE82: TM-score 0.80, RMSD 3.17 Å
- 4BIU chain F against the predicted model P0AE82: TM-score 0.80, RMSD 3.17 Å
- 4BIZ chain F against the predicted model P0AE82: TM-score 0.76, RMSD 3.82 Å
- 4BIZ chain F against the predicted model P0AE82: TM-score 0.76, RMSD 3.82 Å
- 4BIZ chain B against the predicted model P0AE82: TM-score 0.76, RMSD 4.05 Å
- 4BIZ chain B against the predicted model P0AE82: TM-score 0.76, RMSD 4.05 Å
- 4BIY chain B against the predicted model P0AE82: TM-score 0.76, RMSD 3.84 Å
- 4BIY chain B against the predicted model P0AE82: TM-score 0.76, RMSD 3.84 Å
Elsewhere
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