UniProt P0AE20
Methionine aminopeptidase (P0AE20)
Methionine aminopeptidase (UniProt P0AE20), EC 3.4.11.18: 2 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 5 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P0AE20
- Protein
- Methionine aminopeptidase
- EC
- 3.4.11.18
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 5 · 1 record with a druggable one
Structures
3 records of P0AE20 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4Z7M | Novel Inhibitors of Bacterial Methionine Aminopeptidase with Broad-Spectrum Biochemical Activity | x-ray diffraction | A, B | MN, 4L9 | 5 (best 0.66) |
| 4Z7M | Novel inhibitors of bacterial methionine aminopeptidase with broad- spectrum biochemical activity | x-ray diffraction | A, B | — | — |
| P0AE20 | AlphaFold monomer V2.0 prediction for methionine aminopeptidase (P0AE20) | predicted | A | — | — |
Ligands
Experiment against prediction
- 4Z7M chain B against the predicted model P0AE20: TM-score 1.00, RMSD 0.37 Å
- 4Z7M chain A against the predicted model P0AE20: TM-score 1.00, RMSD 0.39 Å
- 4Z7M chain A against the predicted model P0AE20: TM-score 1.00, RMSD 0.39 Å
Elsewhere
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