UniProt P0AE07

Multidrug efflux pump subunit AcrA (P0AE07)

Multidrug efflux pump subunit AcrA (UniProt P0AE07): 4 experimental structures and 1 predicted model on GenesisL1, 11 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.

UniProt: P0AE07
Protein: Multidrug efflux pump subunit AcrA
Experimental structures: 4
Predicted models: 1
Pockets: 11 · 1 record with a druggable one

Structures

5 records of P0AE07 in the MolNFT archive: 4 experimental, 1 predicted.

Entry	Title	Method	Chains	Ligands	Pockets
5O66	Asymmetric AcrABZ-TolC	electron microscopy	D, E, F, G, H, I	—	—
5O66	Asymmetric acrabz-tolc	electron microscopy	D, E, F, G, H, I	—	—
5V5S	multi-drug efflux; membrane transport; RND superfamily; Drug resistance	electron microscopy	D, E, F, G, H, I	—	11 (best 0.87)
5V5S	Multi-drug efflux; membrane transport; rnd superfamily; drug resistance	electron microscopy	D, E, F, G, H, I	—	—
P0AE07	AlphaFold monomer V2.0 prediction for multidrug efflux pump subunit acra (P0AE07)	predicted	A	—	—

Experiment against prediction

5O66 chain E against the predicted model P0AE07: TM-score 0.88, RMSD 2.58 Å
5O66 chain E against the predicted model P0AE07: TM-score 0.88, RMSD 2.58 Å
5O66 chain I against the predicted model P0AE07: TM-score 0.88, RMSD 2.58 Å
5O66 chain I against the predicted model P0AE07: TM-score 0.88, RMSD 2.58 Å
5O66 chain G against the predicted model P0AE07: TM-score 0.88, RMSD 2.59 Å
5O66 chain G against the predicted model P0AE07: TM-score 0.88, RMSD 2.59 Å
5V5S chain I against the predicted model P0AE07: TM-score 0.86, RMSD 2.84 Å
5V5S chain I against the predicted model P0AE07: TM-score 0.86, RMSD 2.84 Å
5V5S chain G against the predicted model P0AE07: TM-score 0.86, RMSD 2.89 Å
5V5S chain G against the predicted model P0AE07: TM-score 0.86, RMSD 2.89 Å

Elsewhere

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.