UniProt P0AC30
Cell division protein FtsX (P0AC30)
Cell division protein FtsX (UniProt P0AC30): 7 experimental structures and 1 predicted model on GenesisL1, 65 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P0AC30
- Protein
- Cell division protein FtsX
- Experimental structures
- 7
- Predicted models
- 1
- Pockets
- 65 · 5 records with a druggable one
Structures
8 records of P0AC30 in the MolNFT archive: 7 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6TPI | EnvC bound to the FtsX periplasmic domain | x-ray diffraction | B, C | — | — |
| 6TPI | Envc bound to the ftsx periplasmic domain | x-ray diffraction | B, C | — | — |
| 8HD0 | Cell divisome sPG hydrolysis machinery FtsEX-EnvC | electron microscopy | C, D | — | 11 (best 0.85) |
| 8W6I | Cryo-EM structure of Escherichia coli Str K12 FtsEX complex with ATP-gamma-S in peptidisc | electron microscopy | C, A | — | 15 (best 0.86) |
| 8W6J | Cryo-EM structure of Escherichia coli Str K12 FtsE(E163Q)X/EnvC complex with ATP in peptidisc | electron microscopy | A, C | — | 18 (best 0.81) |
| 8X61 | Cryo-EM structure of ATP-bound FtsE(E163Q)X | electron microscopy | C, D | — | 10 (best 0.83) |
| 8Y3X | Cell divisome sPG hydrolysis machinery FtsEX-EnvC | electron microscopy | C, D | — | 11 (best 0.85) |
| P0AC30 | AlphaFold monomer V2.0 prediction for cell division protein ftsx (P0AC30) | predicted | A | — | — |
Experiment against prediction
- 6TPI chain C against the predicted model P0AC30: TM-score 0.93, RMSD 1.05 Å
- 6TPI chain C against the predicted model P0AC30: TM-score 0.93, RMSD 1.05 Å
- 6TPI chain B against the predicted model P0AC30: TM-score 0.92, RMSD 1.31 Å
- 6TPI chain B against the predicted model P0AC30: TM-score 0.92, RMSD 1.31 Å
- 8X61 chain D against the predicted model P0AC30: TM-score 0.91, RMSD 1.88 Å
- 8X61 chain C against the predicted model P0AC30: TM-score 0.90, RMSD 1.87 Å
- 8HD0 chain D against the predicted model P0AC30: TM-score 0.87, RMSD 2.58 Å
- 8Y3X chain D against the predicted model P0AC30: TM-score 0.87, RMSD 2.58 Å
- 8W6J chain A against the predicted model P0AC30: TM-score 0.82, RMSD 3.14 Å
- 8W6J chain C against the predicted model P0AC30: TM-score 0.82, RMSD 3.19 Å
Elsewhere
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