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UniProt P0A9G6

Isocitrate lyase (P0A9G6)

Isocitrate lyase (UniProt P0A9G6), EC 4.1.3.1: 2 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 20 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.

UniProt
P0A9G6
Protein
Isocitrate lyase
EC
4.1.3.1
Experimental structures
2
Predicted models
1
Ligands
3
Pockets
20 · 1 record with a druggable one

Structures

3 records of P0A9G6 in the MolNFT archive: 2 experimental, 1 predicted.

EntryTitleMethodChainsLigandsPockets
1IGWCrystal Structure of the Isocitrate Lyase from the A219C mutant of Escherichia colix-ray diffractionA, B, C, DHG, MG, PYR20 (best 0.85)
1IGWCrystal structure of the isocitrate lyase from the A219C mutant of escherichia COLIx-ray diffractionA, B, C, D——
P0A9G6AlphaFold monomer V2.0 prediction for isocitrate lyase (P0A9G6)predictedA——

Ligands

  • HG · Mercury (II) ion · in 1 record
  • MG · Magnesium ion · in 1 record
  • PYR · Pyruvic acid · in 1 record

Experiment against prediction

Elsewhere

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